Definition
US FDA substance register · UNII RAO49190JV · registered name 1,6-HEXANEDIOL DIMETHACRYLATE · single chemical substance
Hexanediol Dimethacrylate is the organic compound that conforms to the formula:
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 6606-59-3
- EC No.EU chemical inventory number
- 229-551-7
- DTXSIDUS EPA chemical ID
- DTXSID9044455
- DTXCIDUS EPA compound ID
- DTXCID7024455
- IUPAC
- Hexane-1,6-diyl bis(2-methylprop-2-enoate)
- Molecular formula
- C14H22O4
- Molecular weight
- 254.326 g/mol
Measured properties
- Appearance
- liquid
- Melting/freezing point
- 2.11 ℃(1013 hPa)
- Initial boiling point and range
- 190 ℃(1013 hPa)
- Vapour pressure
- 0.64 ㎩ (25 °C, calc.)
- Water solubility
- 23 ㎎/ℓ
- Relative density
- 0.998
- n-Octanol/water partition coefficient (Kow)
- 4.08 (OECD TG 117)
- Auto-ignition temperature
- 275 ℃ (1013 hPa)
- Viscosity
- 3.69 (OECD TG 114, 40 °C)
- Molecular weight
- 254.324
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 7 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Monomers3
- Intermediate2
- Softener and conditioner1
- Photosensitive agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: according to Appraisal of the Safety of Chemicals in foods, drugs and cosmetics, FDA Draize (1959) according to - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Appraisal of the safety of chemicals in foods, druge and cosmetics, by the Staft of the Division of Pharmacology, US FDA, Bewertung von Augen-Lasionen nach Draize (1959) according to other guideline: US FHSA Federal regulation: 16 CFR 1500.42 equivalent or similar to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
Linked databases 12
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- Tlooto literature search 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata