Ingredient Dictionary

HEXENE

1-hexene is an alkene that is hexane carrying a double bond at position 1.

Definition

1-hexene is an alkene that is hexane carrying a double bond at position 1.

Source: PubChem

US FDA substance register · UNII B38ZZ8C206 · registered name 1-HEXENE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Base that dissolves other ingredientsSOLVENT

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

HEXENEINCI헥센Korean label name (MFDS standard)1-HexeneSynonym

CAS No.chemical registry number: 592-41-6
EC No.EU chemical inventory number: 209-753-1
DTXSIDUS EPA chemical ID: DTXSID4025402
DTXCIDUS EPA compound ID: DTXCID105402

IUPAC: Hex-1-ene
Molecular formula: C6H12
Molecular weight: 84.162 g/mol

Measured properties

Appearance: 1-hexene appears as a clear colorless liquid with a petroleum like odor. Flash point -9 °F. Less dense than water and insoluble in water. Vapors heavier than air. Used as a solvent, paint thinner, and chemical reaction medium. · CBI, Liquid
Boiling point: 146.3 °F at 760 mmHg (USCG, 1999) · 63.4 °C @ 760 mm Hg
Melting point: -219.6 °F (USCG, 1999) · -139.7 °C
Solubility: Very sol in ethanol, ethyl ether, benzene, and petroleum ether · In water, 50 mg/l at 25 °C
Density: 0.673 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.6731 @ 20 °C/4 °C
Viscosity: 0.39 sq mm/s
Melting/freezing point: -140 ℃
Initial boiling point and range: 63 ℃
Flash point: -26 ℃(c.c.)
Upper/lower flammability or explosive limits: 6.9 / 1.2 %
Vapour pressure: 18.7 ㎪ (20℃)
Water solubility: 0.005 ( 20℃)
Vapour density: 2.9
Relative density: 0.7
n-Octanol/water partition coefficient (Kow): 3.39
Auto-ignition temperature: 253 ℃
Molecular weight: 84.2

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 17 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Monomers4
Intermediate3
Fuel2
Processing aids not otherwise specified2
Lubricating agent2
Viscosity modifier2
Solvent1
Surfactant (surface active agent)1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

18 skin studies and 7 eye studies are on record.

Classed as highly irritating3Classed as moderate3Classed as low33

The studies disagree (the most common conclusion covers 8%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 25 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to EPA OTS 798.4470 (Acute Dermal Irritation) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labelling Act (FHSLA) according to
Not classified
Skin Irritation · Screening
Not classified
Skin Sensitization · Screening
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act (FHSLA) according to
Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Category 6.3B (Category 3)
Skin Irritation · Read Across
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: U.S. EPA FIFRA (Pesticide Assessment Guidelines Subdivision F/TSCA (798.4470) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Magnusson and Kligman
Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to EPA OTS 798.4470 (Acute Dermal Irritation) according to
Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substance Labelling Act (FHSLA) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act (FHSLA) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labelling Act according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Not classified
Eye Irritation · Screening
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Register 28 (110), 6.6.1963. paragraph 191.12 Test for eye irritants. according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to