4-hexylbenzene-1,3-diol is a member of resorcinols.
How much products actually contain
No product states its amount yet.
Of the products containing it, 15 list it before the 1% line and 13 after it (usually 1% or less).
Products using this ingredient
12 of 28 confirmed · likeliest to carry enough first · See all 28
DermalogicaDermalogica post-breakout fix
MuradMurad InvisiScar Resurfacing Treatment
MuradMurad InvisiScar Resurfacing Treatment Larger Size
MuradMurad Retinol Youth Renewal Face Oil Drops
HourglassHourglass Equilibrium Resurfacing Retinoid Treatment
DermalogicaDermalogica powerbright overnight cream
MuradMurad Cellular Hydration Repair Face Oil Drops
DermalogicaDermalogica powerbright dark spot serum
Peach & LilyPeach & Lily Pure Radiance Brightening Eye Cream
DominasCream Rx 30ml
MuradMurad Vita-C Glycolic Serum
MuradMurad Vita-C Glycolic Serum Deluxe Travel Size
Definition
4-hexylbenzene-1,3-diol is a member of resorcinols.
Source: PubChem
US FDA substance register · UNII R9QTB5E82N · registered name Hexylresorcinol · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ヘキシルレゾルシノール: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 136-77-6
- EC No.EU chemical inventory number
- 205-257-4
- DTXSIDUS EPA chemical ID
- DTXSID1020699
- DTXCIDUS EPA compound ID
- DTXCID10699
- IUPAC
- 4-Hexylbenzene-1,3-diol
- Molecular formula
- C12H18O2
- Molecular weight
- 194.274 g/mol
Measured properties
- Appearance
- P-hexylresorcinol appears as pale-yellow viscous liquid (that becomes solid on standing at room temperature) or a peach colored powder. Pungent faintly fatty odor. Sharp astringent taste. (NTP, 1992) · White powder
- Odour
- Pungent odor
- Boiling point
- 631 °F at 760 mmHg (NTP, 1992) · 178-180 °C at 6.7 mm Hg, 198-100 °C at 13-14 mm HG, 333-335 °C at 760 mm Hg
- Melting point
- 154 to 156 °F (NTP, 1992) · 62 to 67 °C
- Solubility
- less than 1 mg/mL at 73 °F (NTP, 1992) · Freely soluble in ether and acetone, very slightly soluble in water
- Melting/freezing point
- 68 ℃
- Initial boiling point and range
- 333 ℃
- Flash point
- 159 ℃
- Vapour pressure
- (6E-5 mmHg (25 C))
- Water solubility
- (0.05%)
- n-Octanol/water partition coefficient (Kow)
- 3.45
- Molecular weight
- 194.27
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 7 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Biocide5
- Pharmaceutical (EPA)2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- SkinIrr2
Skin Irritation · QSAR Predicted - SkinSens1
Skin Sensitization · QSAR Predicted - Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Acrisorcin · 2020
- Effects of 4-hexylresorcinol administration on the submandibular glands in a growing rat model · 2022
- 4-Hexylresorcinol a New Molecule for Cosmetic Application · 2018
- Superior even skin tone and anti‐ageing benefit of a combination of 4‐hexylresorcinol and niacinamide · 2018
- Quantitative Assessment of Antimicrobial Activity of PLGA Films Loaded with 4-Hexylresorcinol · 2018
Linked databases 21
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports
- Wikidata
- Wikipedia · English · Japanese · Chinese