Definition
US FDA substance register · UNII G6U2GR91JI · registered name 12-OXAHEXADECANOLIDE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 6707-60-4
- EC No.EU chemical inventory number
- 229-755-6
- DTXSIDUS EPA chemical ID
- DTXSID4047705
- DTXCIDUS EPA compound ID
- DTXCID2027703
- IUPAC
- 1,6-Dioxacycloheptadecan-7-one
- Molecular formula
- C15H28O3
- Molecular weight
- 256.386 g/mol
Measured properties
- Water solubility
- 1.433 ㎎/ℓ
- n-Octanol/water partition coefficient (Kow)
- 4.9
- Molecular weight
- 256.43
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance3
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: Skin irritation and capacity of allergenic sensitization determined by Open Epicutaneous test on Guinea Pigs according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: The method of procedure is that suggested by Dr. Draize and described in "Appraisal of the safety of chemicals in foods, drugs amd cosmetics" published by the Association of Food and Drug Officials of the United States. according to
Source: US EPA CompTox dashboard
Linked databases 11
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata