Ingredient Dictionary

HYDROCHLOROFLUOROCARBON 22

Chlorodifluoromethane is a hydrochlorofluorocarbon.

Definition

Chlorodifluoromethane is a hydrochlorofluorocarbon.

Source: PubChem

US FDA substance register · UNII ZFO627O6CN · registered name HYDROCHLOROFLUOROCARBON 22 · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Pushes the product out (aerosol)PROPELLANT

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer · Related EU regulation: (EC) 2009/1005

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

HYDROCHLOROFLUOROCARBON 22INCI하이드로클로로플루오로카본22Korean label name (MFDS standard)Methane, chlorodifluoro-Synonym

CAS No.chemical registry number: 75-45-6
EC No.EU chemical inventory number: 200-871-9
DTXSIDUS EPA chemical ID: DTXSID6020301
DTXCIDUS EPA compound ID: DTXCID60301

IUPAC: Chlorodi(fluoro)methane
Molecular formula: CHClF2
Molecular weight: 86.47 g/mol

Measured properties

Appearance: Chlorodifluoromethane is a colorless gas with an ethereal odor. It is shipped as a liquefied gas under its own vapor pressure. It is noncombustible. It can asphyxiate by the displacement of air. Contact with the liquid can cause frostbite. Toxic gases can be produced in fires involving this material. Exposure of the container to prolonged heat or fire may cause it to rupture violently and rocket. · Liquid
Odour: Nearly odorless · Like carbon tetrachloride
Boiling point: -40.9 °F at 760 mmHg (USCG, 1999) · -40.8 °C
Melting point: -231 °F (NIOSH, 2024) · -157.42 °C
Solubility: 0.3 % at 77 °F (NIOSH, 2024) · Solubility: 0.14 g/L water at 122 °F at 14.7 psia
Density: 1.41 at -40 °F (USCG, 1999) - Denser than water, will sink · 1.194 at 25 °C
Stability: The product is stable.
Viscosity: 0.23 mN/sec/sq m at 25 °C (liquid), 0.013 mN/sec/sq m at 25 °C (gas) · 0.23/0.013 (Liquid/Gas)
Colour: colourless
Initial boiling point and range: -40.8 ℃
Flammability (solid, gas): not flammable
Vapour pressure: 7250 ㎜Hg (25℃)
Water solubility: 3 (at 25℃, g/L)
Vapour density: 3
Relative density: 3.595 kg/m³ (293.15 K)
n-Octanol/water partition coefficient (Kow): 1.08
Auto-ignition temperature: 632 ℃
Decomposition temperature: (-6.5704E+07 J/kmol)
Molecular weight: 86.5

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 11 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Refrigerants3
Foamant3
Intermediate2
Propellants, non-motive (blowing agents)1
Insulators1
Sealant (barrier)1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies

Not classified
Skin Irritation · Screening
Classification not possible
Skin Sensitization · Screening
Category 2B
Eye Irritation · Screening