Hydroquinone is a benzenediol comprising benzene core carrying two hydroxy substituents para to each other.
产品中实际含有多少
暂无产品标示该成分含量。
含该成分的产品中,88 款将其列在 1% 线之前,1 款列在之后(通常不超过 1%)。
含有此成分的产品
已确认 89 款中的 12 款 · 按含量充足程度排序 · 查看全部 89 款
ORLYORLY Nail Tip Primer
ORLYORLY Nail Tip Primer - 0.6fl oz
ORLYORLY Astral Projection - Gel Nail Color
ORLYORLY Gotta Bounce - Gel Nail Color
ORLYORLY Midnight Oasis - Gel Nail Color
ORLYORLY Positive Coral-ation - Gel Nail Color
ORLYORLY 'Twas The Night 6PIX Gel Nail Color
ORLYORLY Act of Folly - Gel Nail Color
ORLYORLY Air Of Mystique - Gel Nail Color
ORLYORLY Aqua Aura 6PIX Gel Nail Color
ORLYORLY Artist's Garden - Gel Nail Color
ORLYORLY Ascension - Gel Nail Color
定义
Hydroquinone is a benzenediol comprising benzene core carrying two hydroxy substituents para to each other. It has a role as an antioxidant, a cofactor, a carcinogenic agent, a mouse metabolite, a human xenobiotic metabolite, an Escherichia coli metabolite and a skin lightening agent. It is a benzenediol and a member of hydroquinones.
来源: PubChem
美国FDA 物质登记 · UNII XV74C1N1AE · 登记名称 Hydroquinone · 单一化学物质
Hydroquinone is the aromatic organic compound that conforms to the formula:
化妆品中的作用
安全与法规参考
- 禁用
- 阿根廷 · 巴西 · 英国
- 限用·禁用
- 阿根廷 · 巴西 · 韩国 · 中国
- 限用
- 英国
来源: 东盟化妆品指令 · 欧盟化妆品法规 · 韩国食药处 化妆品法规信息 · 英国化妆品法规 · 加拿大禁用·限用成分清单
东盟
- Field of application and/or use : Artificial nail systems
- Maximum authorised concentration in the finished cosmetic product : 0.02% after mixing for use
- Other limitations and requirements : Professional use only
- Conditions of use and warning which must be printed on the labels : • For professional use only • Avoid skin contact • Read directions for use carefully
加拿大
- Conditions of Use by product type : (a) Oxidizing colouring agent for hair dyes (b) Nail products (c) Cyanoacrylate adhesive products for eyelash and eyebrow extensions
- Maximum Concentration Permitted : (a) 0.3% (b) 0.1% If hydroquinone and p-hydroxyanisole are used in the same product, the total concentration of the 2 ingredients may not exceed 0.1% (c) 0.1%
- Warnings and Cautionary Statements: (to the effect of) : (a) "Avoid skin contact", "Do not use to dye eyelashes or eyebrows", "Rinse eyes immediately if the product comes into contact with eyes" (b) "Avoid skin contact."; "Read directions carefully before using." (c) "Avoid skin contact."; "Read directions carefully before using."
欧盟
- Product Type, body parts : Artificial nail systems
- Maximum concentration in ready for use preparation : 0.02% (after mixing for use)
- Other : Professional use
- Wording of conditions of use and warnings : - For professional use only - Avoid skin contact - Read directions for use carefully
来源: 韩国食药处 化妆品法规信息
韩国有毒物质 GHS 分类: 危险 · H410 (第1类) · H400 (第1类) · H351 (第2类) · 另有 4 项
欧盟化妆品法规 附录III(限用物质) 第14项 · 最高浓度 0.02% (after mixing for use) · 适用 Artificial nail systems
来源: 欧盟限用成分(附录III)
欧盟化妆品法规 附录II(禁用物质) 第1339项
来源: 欧盟禁用成分(附录II)
Restriction II/1339 III/14 · Other restriction: ban substances that deplete the ozone layer
来源: 欧盟 CosIng 成分清单
Reviewed by CIR: Final Report: Amended Safety Assessment of Hydroquinone as Used in Cosmetics
来源: 美国CIR 安全性评估
Reviewed by CIR: Final Report on the Safety Assessment of Hydroquinone and Pyrocatechol (Pyrocatechol has been Amended. IJT 16(S1) 11-58 1997.) (Hydroquinone has an Addendum. JACT 13(3) 167-230 1994.)
来源: 美国CIR 安全性评估
Reviewed by CIR: Final Amended Safety Assessment of Hydroquinone as Used in Cosmetics
来源: 美国CIR 安全性评估
Reviewed by CIR: Addendum to the Final Report on the Safety Assessment of Hydroquinone
来源: 美国CIR 安全性评估
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 ハイドロキノン: 本品は、次の化学式で表される芳香族化合物である。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
- CAS No.化学物质登记号
- 123-31-9
- EC No.欧盟化学品目录编号
- 204-617-8
- DTXSID美国EPA化学品编号
- DTXSID7020716
- DTXCID美国EPA化合物编号
- DTXCID70716
- IUPAC
- Benzene-1,4-diol
- 分子式
- C6H6O2
- 分子量
- 110.112 g/mol
实测物性
- 性状
- Hydroquinone appears as light colored crystals or solutions. May irritate the skin, eyes and mucous membranes. Mildly toxic by ingestion or skin absorption. · Large Crystals, Other Solid, Dry Powder, Liquid
- 气味
- Odorless · 无臭
- 沸点
- 545 to 549 °F at 760 mmHg (EPA, 1998) · 285-287
- 熔点
- 338 to 340 °F (EPA, 1998) · 170-171
- 溶解性
- 10 to 50 mg/mL at 68 °F (NTP, 1992) · 6.72g/L at 20 deg C
- 密度
- 1.332 at 59 °F (EPA, 1998) - Denser than water, will sink
- pH
- 4
- 熔点/凝固点
- 172.3 ℃
- 初沸点和沸程
- 287 ℃
- 闪点
- 165 ℃
- 蒸气压
- 0.0000253 hPa(25℃)
- 溶解度
- 72 g/ℓ(mg/L, 25℃)
- 比重
- 1.33
- 正辛醇/水分配系数(Kow)
- 0.59
- 自燃温度
- 515 ℃(at 1013 hPa)
- 分子量
- 110.1114
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 25 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Monomers5
- Fragrance3
- Dye3
- Antioxidant2
- Photosensitive agent2
- Intermediate2
- Processing aids not otherwise specified2
- Stabilizing agent1
其余用途 5 项
- Reducing agent1
- Bleaching agent1
- Catalyst1
- Chemical reaction regulator1
- Flavouring and nutrient1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 10 项、眼部试验 5 项。
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 15 项试验
- Skin Sens. 1
Skin Sensitization · Screening - Skin sensitization - Category 1
Skin Sensitization · Screening - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · equivalent or similar to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Not classified
Skin Irritation · Screening - Category 1
Skin Sensitization · Screening - Skin Sens. 1
Skin Sensitization · Authoritative - Category 6.5B (Category 1)
Skin Sensitization · Read Across - Category 6.3A (Category 2)
Skin Irritation · Read Across - Sh
Skin Sensitization · Authoritative - Serious eye damage/eye irritation - Category 2
Eye Irritation · Screening - Eye Dam. 1
Eye Irritation · Authoritative - Eye Dam. 1
Eye Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across - Category 1
Eye Irritation · Screening
来源: 美国EPA CompTox
相关文献
- The Impact of Hydroquinone on Kidney Health · 2025
- Hyperpigmentation: Looking beyond hydroquinone · 2022
- Nail discoloration after use of hydroquinone · 2016
- Hydroquinone: its value and safety. Commentary on the US FDA proposal to remove hydroquinone from the over-the-counter market · 2007
- The safety of hydroquinone · 2006
关联数据库 27
- 澳大利亚工业化学品名录(AICIS)
- 东盟化妆品指令
- 韩国安全保健公团 安全数据表
- 韩国食药处 化妆品法规信息 2 3 4
- 韩国有毒物质 GHS 信息(环境公团)
- 加拿大禁用·限用成分清单
- 美国CIR 安全性评估 2 3 4 5
- 美国EPA 化学品数据库(DSSTox)
- 美国EPA CompTox 2
- 美国FDA 物质登记(GSRS)
- 美国FDA 物质识别码(UNII)
- 美国NTP 毒理学报告
- 欧盟 CosIng 成分清单 2
- 欧盟化妆品法规
- 欧盟禁用成分(附录II)
- 欧盟限用成分(附录III)
- 日本化妆品工业联合会标示名称
- 英国化妆品法规 2
- 中国已使用化妆品原料目录(IECIC)
- ChEBI
- IARC 致癌性分类
- NIST 化学网络手册
- PubChem 2
- Tlooto 学术文献检索 2 3 4 5
- UniChem 化学物质统一 ID
- Wikidata
- Wikipedia · 韩语 · 英语 · 日语 · 中文