Ingredient Dictionary

HYDROXYBENZALDEHYDE

4-hydroxybenzaldehyde is a hydroxybenzaldehyde that is benzaldehyde substituted with a hydroxy group at position C-4.

Definition

4-hydroxybenzaldehyde is a hydroxybenzaldehyde that is benzaldehyde substituted with a hydroxy group at position C-4. It has a role as an EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor, a mouse metabolite and a plant metabolite.

Source: PubChem

US FDA substance register · UNII O1738X3Y38 · registered name 4-Hydroxybenzaldehyde · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Listed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCEGives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

HYDROXYBENZALDEHYDEINCIBenzaldehyde, 4-hydroxy-Synonym

CAS No.chemical registry number: 123-08-0
EC No.EU chemical inventory number: 204-599-1
DTXSIDUS EPA chemical ID: DTXSID8059552
DTXCIDUS EPA compound ID: DTXCID7033787

IUPAC: 4-Hydroxybenzaldehyde
Molecular formula: C7H6O2
Molecular weight: 122.123 g/mol

Measured properties

Appearance: solid
Melting/freezing point: 116 ℃
Initial boiling point and range: 310 ℃
Flash point: 101 ℃
Upper/lower flammability or explosive limits: 8.4 / 1.4 %
Vapour pressure: 0.02 ㎜Hg (25 C)
Relative density: 1.129
n-Octanol/water partition coefficient (Kow): 1.36
Auto-ignition temperature: 450 ℃
Molecular weight: 122.12

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Flavouring and nutrient2
Fragrance2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies

SkinSens1
Skin Sensitization · QSAR Predicted
Category 6.3A (Category 2)
Skin Irritation · Read Across
Category 6.4A (Category 2A)
Eye Irritation · Read Across