2-hydroxyoctanoic acid is a hydroxy fatty acid that is caprylic (octanoic) acid substituted by a hydroxy group at position 2.
Definition
2-hydroxyoctanoic acid is a hydroxy fatty acid that is caprylic (octanoic) acid substituted by a hydroxy group at position 2. It is functionally related to an octanoic acid. It is a conjugate acid of a 2-hydroxyoctanoate.
Source: PubChem
US FDA substance register · UNII 0R6X0G0S8A · registered name HYDROXYCAPRYLIC ACID · single chemical substance
Cosmetic roles
Safety & regulatory references
Canada
- Conditions of Use by product type : (a) Products for use on the skin for consumer use. Manufacturer or importer to provide pH levels. (b) Products for use on the skin for professional use: Manufacturer must provide Health Canada with evidence of safety including: 1. pH levels 2. AHA concentrations 3. Directions for use 4. Clinical studies demonstrating minimal skin irritation (c) Products intended to be diluted in bath water may contain levels of AHAs exceeding 10% (d) Other cosmetics (e) Any cosmetics
- Maximum Concentration Permitted : (a) Between 3% and 18% total mono-AHA equivalents with a pH equal to or greater than 3.5 (b) Between 18% and 30% total mono-AHA equivalents and/or a pH between 3.0 to 3.5 (d) Between 3% and 30% total mono-AHA equivalents with a pH equal to or greater than 3.0 (e) 3%
- Warnings and Cautionary Statements: (to the effect of) : (a) and (b) : "Use only as directed", "Avoid contact with the eyes", "If irritation persists, discontinue use and consult a physician", "It is recommended that prior to exposure to the sun, users cover areas where AHAs have been applied with sunscreen" Product labels should contain appropriate directions regarding frequency and/or duration of use. (b only) "For professional use only" (d) "Use only as directed", "Avoid contact with eyes", "Discontinue use if rash or irritation occurs"
Taiwan
- Maximum concentration : pH≧3.5;
- pH≥3.5;
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Final Report: Safety Assessment of Fatty Acids and Fatty Acid Salts as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ヒドロキシカプリル酸: 本品は、次の化学式で表されるヒドロキシ脂肪酸である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 617-73-2
- EC No.EU chemical inventory number
- 210-524-3
- DTXSIDUS EPA chemical ID
- DTXSID80862300
- DTXCIDUS EPA compound ID
- DTXCID50811087
- IUPAC
- 2-Hydroxyoctanoic acid
- Molecular formula
- C8H16O3
- Molecular weight
- 160.213 g/mol
Measured properties
- Melting/freezing point
- 70 ℃
- Water solubility
- 15720 ㎎/ℓ
- n-Octanol/water partition coefficient (Kow)
- 1.81
- Molecular weight
- 160.211
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
Source: US EPA CompTox dashboard
Linked databases 18
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- PubChem
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata