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Ingredients

Ingredient Dictionary

HYDROXYDECYL UBIQUINONE

Idebenone is a member of the class of 1,4-benzoquinones which is substituted by methoxy groups at positions 2 and 3, by a methyl group at positions 5, and by a 10-hydroxydecyl group at positions 6.

Molecular structure

How much products actually contain

6 products state the amountmedian 0.1%

  • under 0.01% 1
  • 0.01–0.1% 1
  • 0.1–1% 4
  • 1% or more 0

Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.

Of the products containing it, 12 list it before the 1% line and 63 after it (usually 1% or less).

Products using this ingredient

12 of 75 confirmed · likeliest to carry enough first · See all 75

Definition

Idebenone is a member of the class of 1,4-benzoquinones which is substituted by methoxy groups at positions 2 and 3, by a methyl group at positions 5, and by a 10-hydroxydecyl group at positions 6. Initially developed for the treatment of Alzheimer's disease, benefits were modest; it was subsequently found to be of benefit for the symptomatic treatment of Friedreich's ataxia. It has a role as a ferroptosis inhibitor and an antioxidant. It is a member of 1,4-benzoquinones and a primary alcohol.

Source: PubChem

US FDA substance register · UNII HB6PN45W4J · registered name IDEBENONE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

6-(10-Hydroxydecyl) Ubiquinone

Cosmetic roles

Slows spoilage by oxygenANTIOXIDANT

Safety & regulatory references

Reviewed by CIR: Final Report: Safety Assessment of Ubiquinone Ingredients as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ヒドロキシデシルユビキノン: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

HYDROXYDECYL UBIQUINONEINCI하이드록시데실유비퀴논Korean label name (MFDS standard)ヒドロキシデシルユビキノンJapanese labelling name
CAS No.chemical registry number
58186-27-9
DTXSIDUS EPA chemical ID
DTXSID0040678
DTXCIDUS EPA compound ID
DTXCID8020678
IUPAC
2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
Molecular formula
C19H30O5
Molecular weight
338.444 g/mol

What products actually use it for

What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Antioxidant2

Source: US EPA CompTox dashboard

Related literature

Linked databases 17