成分词典

HYDROXYETHOXY AMINOPYRAZOLOPYRIDINE HCL

定义

Hydroxyethoxy Aminopyrazolopyridine HCl is the organic compound

染发HAIR DYEING

来源: 东盟化妆品指令 · 欧盟化妆品法规 · 韩国食药处化妆品法规信息 · 台湾FDA 化妆品法规 · 英国化妆品法规

东盟

Field of application and/or use : Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Other limitations and requirements : After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2.0% The direction for use “wear suitable gloves” must be included in label or leaflet text.
Conditions of use and warning which must be printed on the labels : To be printed on the label: “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Do not use to dye eyelashes or eyebrows.”

欧盟

Product Type, body parts : Hair dye substance in oxidative hair dye products
Other : after mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,0 %
Wording of conditions of use and warnings : The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.

欧盟化妆品法规附录III（限用物质）第302项 · 适用 Hair dye substance in oxidative hair dye products

Restriction III/302 · SCCS opinion: Opinion on Hydroxyethoxy aminopyrazolopyridine HCl

详细资料——标示名称、识别编号、物性、试验记录、文献

HYDROXYETHOXY AMINOPYRAZOLOPYRIDINE HCLINCI하이드록시에틸아미노피라졸피리딘에이치씨엘韩国标示名称（食药处标准名）

IUPAC: 2-[(3-Aminopyrazolo[1,5-a]pyridin-2-yl)oxy]ethan-1-ol--hydrogen chloride (1/1)
分子式: C9H12ClN3O2
分子量: 229.66 g/mol

这是向美国 EPA 申报含该成分的 1 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。

记录有皮肤试验 2 项、眼部试验 1 项。

归类为刺激性高1 项

试验结论基本一致（100%）。这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。

查看全部 3 项试验

Ambiguous
skin corrosion: in vitro / ex vivo · Screening · OECD Guideline 439 (In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method) equivalent or similar to
High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay)
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to