Ethylzingerone is a methyl ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at positions 3 and 4 by ethoxy and hydroxy groups, respectively.
定義
米国FDA 物質登録 · UNII TH7XI54W45 · 登録名 4-(3-ETHOXY-4-HYDROXYPHENYL)-2-BUTANONE · 単一の化学物質
Ethylzingerone is a methyl ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at positions 3 and 4 by ethoxy and hydroxy groups, respectively. It is a preservative with antimicrobial activity and a good safety profile that has been approved for use in cosmetics. It is structurally similar to zingerone, a phytochemical found in the root of the ginger plant Zingiber officinale. It has a role as an antimicrobial cosmetic preservative, an antibacterial agent and an antifungal agent. It is a member of phenols, an aromatic ether and a methyl ketone.
出典: PubChem
Hydroxyethoxyphenyl Butanone is the organic compound that conforms to the formula:
化粧品での役割
安全性・規制情報
- 許可された防腐剤
- イギリス
出典: ASEAN 化粧品指令 · EU 化粧品規則 · 英国 化粧品規則
アルゼンチン · ブラジル
- Maximum concentration permitted at final product : 0.7%
ASEAN
- Maximum authorised concentration in the finished cosmetic product : 0.7 %
欧州連合
- Product Type, body parts : Allowed for use as a preservative in rinse off, oral care and leave-on cosmetic products at a maximum concentration of 0,7 % in ready for use preparation
- Maximum concentration in ready for use preparation : 0.7%
出典: 韓国食薬処 化粧品規制情報
EU化粧品規則 附属書V(許可防腐剤) 第60項 · 最大濃度 0.7 % · 適用 Allowed for use as a preservative in rinse off, oral care and leave-on cosmetic products at a maximum concentration of 0,7 % in ready for use preparation.
出典: EU 許可防腐剤(附属書V)
SCCS opinion: OPINION ON Ethylzingerone - ‘Hydroxyethoxyphenyl Butanone’ (HEPB) - Cosmetics Europe No P98 – CAS No 569646-79-3 Submission II (eye irritation); OPINION ON Ethylzingerone –‘Hydroxyethoxyphenyl Butanone’ (HEPB)
出典: EU CosIng 成分リスト
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
別名・識別情報
- CAS No.化学物質登録番号
- 569646-79-3
- EC No.EU化学物質目録番号
- 933-435-8
- DTXSID米国EPA化学物質番号
- DTXSID101278928
- DTXCID米国EPA化合物番号
- DTXCID601709429
- IUPAC
- 4-(3-Ethoxy-4-hydroxyphenyl)butan-2-one
- 分子式
- C12H16O3
- 分子量
- 208.257 g/mol
製品が実際に使っている用途
関連文献
- Ethylzingerone, a Novel Compound with Antifungal Activity · 2021
- Opinion of the Scientific Committee on Consumer safety (SCCS) - Opinion on Ethylzingerone - 'Hydroxyethoxyphenyl Butanone' (HEPB) - Cosmetics Europe No P98 - CAS No 569646-79-3 - Submission II (eye irritation). · 2019
- A Green and Rapid Analytical Method for the Determination of Hydroxyethoxyphenyl Butanone in Cosmetic Products by Liquid Chromatography · 2018
- Opinion of the scientific committee on consumer safety (SCCS) - Final version of the opinion on Ethylzingerone - 'Hydroxyethoxyphenyl Butanone' (HEPB) - Cosmetics Europe No P98 - in cosmetic products. · 2017