Definition
US FDA substance register · UNII 49KP498D4O · registered name HYDROXYLAMINE SULFATE · single chemical substance
Bis(Hydroxylammonium) sulphate
Cosmetic roles
Safety & regulatory references
- Banned
- ASEAN · European Union
Source: MFDS (Korea) cosmetic regulatory information
Korea’s toxic-substance GHS classification: Danger · H311 (category 3) · H400 (category 1) · H372 (category 1) · +6 more
Restriction 1223/article 15 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 10039-54-0
- EC No.EU chemical inventory number
- 233-118-8
- DTXSIDUS EPA chemical ID
- DTXSID2025424
- DTXCIDUS EPA compound ID
- DTXCID505424
- IUPAC
- Bis(hydroxyammonium) sulfate
- Molecular formula
- H8N2O6S
- Molecular weight
- 164.13 g/mol
Measured properties
- Appearance
- Hydroxylamine sulfate is a colorless crystalline solid. Contact may cause severe irritation to skin, eyes, and mucous membranes. May be toxic by ingestion. · Liquid, Other Solid, Dry Powder, Large Crystals
- Melting point
- 338 °F (decomposes) (NTP, 1992) · 170 °C
- Solubility
- greater than or equal to 100 mg/mL at 70 °F (NTP, 1992) · Solubility in water, g/100ml at 20 °C: 58.7
- Density
- greater than 1 at 68 °F (USCG, 1999) · 1.88 g/cm³
- Colour
- white
- Melting/freezing point
- 120 ℃
- Water solubility
- 58.7 g/100㎖ (20℃)
- Relative density
- 1.88
- n-Octanol/water partition coefficient (Kow)
- -3.6
- Decomposition temperature
- 120 ℃
- Molecular weight
- 164.14
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 13 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Chemical reaction regulator4
- pH regulating agent2
- Intermediate2
- Reducing agent2
- UV stabilizer1
- Antioxidant1
- Catalyst1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
10 skin studies and 5 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 15 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Skin Irrit. 2
Skin Irritation · Authoritative - Skin Sens. 1
Skin Sensitization · Authoritative - Skin corrosion/irritation - Category 1
Skin Irritation · Screening - Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Category 6.5B (Category 1)
Skin Sensitization · Read Across - Category 1
Skin Sensitization · Screening - Not classified
Skin Irritation · Screening - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Serious eye damage/eye irritation - Category 1
Eye Irritation · Screening - Category 2A
Eye Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across - Eye Irrit. 2
Eye Irritation · Authoritative - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- PubChem
- PubMed
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese