5-hydroxymethylfurfural is a member of the class of furans that is furan which is substituted at positions 2 and 5 by formyl and hydroxymethyl substituents, respectively.
定義
5-hydroxymethylfurfural is a member of the class of furans that is furan which is substituted at positions 2 and 5 by formyl and hydroxymethyl substituents, respectively. Virtually absent from fresh foods, it is naturally generated in sugar-containing foods during storage, and especially by drying or cooking. It is the causative component in honey that affects the presystemic metabolism and pharmacokinetics of GZ in-vivo. It has a role as an indicator and a Maillard reaction product. It is a primary alcohol, a member of furans and an arenecarbaldehyde.
出典: PubChem
米国FDA 物質登録 · UNII 70ETD81LF0 · 登録名 5-(Hydroxymethyl)-2-furaldehyde · 単一の化学物質
Hydroxymethylfurfural is the organic compound that conforms to the formula
化粧品での役割
安全性・規制情報
韓国の有害物質GHS分類なし · 既存化学物質
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
別名・識別情報
- CAS No.化学物質登録番号
- 67-47-0
- DTXSID米国EPA化学物質番号
- DTXSID3030428
- DTXCID米国EPA化合物番号
- DTXCID1010428
- IUPAC
- 5-(Hydroxymethyl)furan-2-carbaldehyde
- 分子式
- C6H6O3
- 分子量
- 126.111 g/mol
測定された物性
- 性状
- Solid with an odor of chamomile flowers, mp = 31.5 deg C, [Merck Index] Beige or yellow hygroscopic solid, mp = 32-35 deg C, [Alfa Aesar MSDS] · Solid
- 臭い
- Odor of chamomile flowers
- 沸点
- BP: 115 °C at 1 mm Hg · 114.00 to 116.00 °C. @ 1.00 mm Hg
- 融点
- 31.5 °C · 35 - 35.5 °C
- 溶解性
- Freely soluble in methanol, ethanol, acetone, ethyl acetate, dimethylformamide. Soluble in ether, benzene, chloroform. Less soluble in carbon tetrachloride. Sparingly soluble in petroleum ether. · Soluble in common organic solvents
- 密度
- 1.2062 g/cu cm at 25 °C
- 融点・凝固点
- 31.5 ℃
- 引火点
- 79 ℃
- 分子量
- 126.12
物質そのものを測定した値です。安全保健公団（KOSHA）の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。
出典: PubChem · 韓国安全保健公団 SDS
製品が実際に使っている用途
米国EPAにこの成分を届け出た製品1件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。
- Flavouring and nutrient1
出典: 米国EPA CompTox
関連文献
- Application of a Next Generation Risk Assessment Framework, Integrated Testing Strategy Defined Approaches and Read-across for Evaluating the Skin Sensitization Potency: Case studies with 5-Hydroxymethylfurfural and 5,5'-Oxydimethylenebis (2-Furfural). · 2026
- The effects of 5-Hydroxymethylfurfural in mitigating transportation stress of large yellow croaker (Larimichthys crocea) · 2025
- 5‐Hydroxymethylfurfural multimers induce pseudo‐allergic reaction through FcεRI at high doses · 2023
- Effect of storage and frying times on stability of acrylamide and 5-hydroxymethylfurfural in fresh and frozen curry puff skins · 2020
- Spatial distributions of furan and 5-hydroxymethylfurfural in unroasted and roasted Coffea arabica beans. · 2019