Is there safety information?

일부 예민한 피부에서는 자극이 있을 수 있으므로 주의가 필요합니다.

Are there usage precautions?

피부 탄력과 수분 유지 콜라겐 합성 촉진 주름 개선 및 피부 강화 효과 (추천 피부타입: 민감성 피부 제외 모든 피부 타입)

All ingredients

Ingredient Dictionary

HYDROXYPROLINE

Trans-4-hydroxy-L-proline is an optically active form of 4-hydroxyproline having L-trans-configuration.

How much products actually contain

No product states its amount yet.

Of the products containing it, 7 list it before the 1% line and 22 after it (usually 1% or less).

Products using this ingredient

12 of 29 confirmed · likeliest to carry enough first · See all 29

Definition

Trans-4-hydroxy-L-proline is an optically active form of 4-hydroxyproline having L-trans-configuration. It has a role as a mouse metabolite, a plant metabolite and a human metabolite. It is a tautomer of a trans-4-hydroxy-L-proline zwitterion.

Source: PubChem

US FDA substance register · UNII RMB44WO89X · registered name Hydroxyproline · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Surfactant that lifts dirtSURFACTANT - CLEANSINGReduces staticANTISTATICKeeps skin in good condition (CosIng catch-all)SKIN CONDITIONINGSoftens hairHAIR CONDITIONING

Safety & regulatory references

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ヒドロキシプロリン: 本品は、次の化学式で表されるアミノ酸である。

Source: JCIA labelling names (Japan)

Names & identifiers

HYDROXYPROLINEINCI하이드록시프롤린Korean label name (MFDS standard)L-Proline, 4-hydroxy-, (4R)-SynonymヒドロキシプロリンJapanese labelling name

CAS No.chemical registry number: 51-35-4
CAS No.chemical registry number: 6912-67-0
EC No.EU chemical inventory number: 200-091-9
DTXSIDUS EPA chemical ID: DTXSID10883225
DTXCIDUS EPA compound ID: DTXCID001022774

IUPAC: (4R)-4-Hydroxy-L-proline
Molecular formula: C5H9NO3
Molecular weight: 131.131 g/mol

Measured properties

Appearance: Solid, [Merck Index] White crystalline powder, [Alfa Aesar MSDS] · Solid
Boiling point: Decomposes
Melting point: 274°C · 274 - 275 °C
Solubility: Soluble in water at 0, 25, 50, and 60 °C · 361 mg/mL at 25 °C
Dissociation constant: pK1′ 1.82 and pK2′ 9.65
Colour: white
Melting/freezing point: 274 ℃
Initial boiling point and range: 355.2 ℃(760mmHg)
Flash point: 168.6 ℃
Vapour pressure: 1.41E-9 ㎜Hg (25°C)
Water solubility: 3.61E+05 ㎎/ℓ (25°C)
Vapour density: 4.526406627545737
Relative density: 0.38 (20°C)
n-Octanol/water partition coefficient (Kow): -3.17
Molecular weight: 131.13

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 10 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Softener and conditioner6
Anti-static agent2
Surfactant (surface active agent)2

Source: US EPA CompTox dashboard