Definition
US FDA substance register · UNII C15K4UUJ1E · registered name HYDROXYMETHYL DIOXOLANONE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 931-40-8
- EC No.EU chemical inventory number
- 213-235-0
- DTXSIDUS EPA chemical ID
- DTXSID90862477
- DTXCIDUS EPA compound ID
- DTXCID00811234
- IUPAC
- 4-(Hydroxymethyl)-1,3-dioxolan-2-one
- Molecular formula
- C4H6O4
- Molecular weight
- 118.088 g/mol
Measured properties
- Appearance
- liquid
- Melting/freezing point
- -70~-60
- Initial boiling point and range
- 239 ℃(102.1 kPa)
- Flash point
- 149.5 ℃(101.3 kPa)
- Vapour pressure
- 0.93 ㎩ ((25℃))
- Water solubility
- &, gt, 1000 g/ℓ ((24℃))
- Relative density
- 1.42 (20 °C)
- n-Octanol/water partition coefficient (Kow)
- -1.39
- Auto-ignition temperature
- 404 ℃ (102.2 kPa)
- Molecular weight
- 118.08
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Ambiguous
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EPA OPPTS 870.2600 (Skin Sensitisation) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Linked databases 13
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese