Definition
US FDA substance register · UNII YO3915897S · registered name HYDROXYPYRIDINONE · single chemical substance
Hydroxypyridinone is the heterocyclic compound that conforms to the formula
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · China · European Union · South Korea · Taiwan · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1249
Restriction II/1249 (hypyridinone and its salts, when used as a substance in hair dye products)
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 822-89-9
- EC No.EU chemical inventory number
- 212-506-0
- DTXSIDUS EPA chemical ID
- DTXSID70231622
- DTXCIDUS EPA compound ID
- DTXCID00154113
- IUPAC
- 1-Hydroxypyridin-2(1H)-one
- Molecular formula
- C5H5NO2
- Molecular weight
- 111.1 g/mol
Measured properties
- Melting/freezing point
- 106.31 ℃
- Initial boiling point and range
- 252.3~ ℃ (760 mmHg)
- Vapour pressure
- 0.00304 ㎜Hg (25 °C)
- Water solubility
- 376200 ㎎/ℓ
- Vapour density
- 3.834956851915775
- n-Octanol/water partition coefficient (Kow)
- -0.64
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Foamant1
- Dye1
Source: US EPA CompTox dashboard
Related literature
- Investigation of complexation behavior of piroctone olamine salt with Fe(III) ions and influence on antifungal activity · 2026
- Novel Iron-Chelator DIBI Inhibits Staphylococcus aureus Growth, Suppresses Experimental MRSA Infection in Mice and Enhances the Activities of Diverse Antibiotics in vitro · 2018
- Hydroxypyridinone and 5-Aminolaevulinic Acid Conjugates for Photodynamic Therapy. · 2017
- The hydroxypyridinone iron chelator CP94 increases methyl-aminolevulinate-based photodynamic cell killing by increasing the generation of reactive oxygen species · 2016
- Enhancing Protoporphyrin IX induced Photodynamic Therapy with a Topical Iron Chelating Agent in a Normal Skin Model · 2016
Linked databases 17
- ASEAN Cosmetic Directive
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- Taiwan FDA cosmetic ingredients
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata