Imidazolidin-2-one is a member of ureas and an imidazolidinone.
Definition
Imidazolidin-2-one is a member of ureas and an imidazolidinone.
Source: PubChem
US FDA substance register · UNII 2K48456N55 · registered name IMIDAZOLIDINONE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 120-93-4
- EC No.EU chemical inventory number
- 204-436-4
- DTXSIDUS EPA chemical ID
- DTXSID0020602
- DTXCIDUS EPA compound ID
- DTXCID20602
- IUPAC
- Imidazolidin-2-one
- Molecular formula
- C3H6N2O
- Molecular weight
- 86.094 g/mol
Measured properties
- Appearance
- CBI, Liquid · White odorless solid, [Hawley] Light yellow crystals, [Aldrich MSDS]
- Melting point
- 131 °C
- Solubility
- VERY SOL IN WATER & IN HOT ALC, DIFFICULTLY SOL IN ETHER · SLIGHTLY SOL IN CHLOROFORM
- pH
- 9~11 (100 g/ℓ, 20℃)
- Melting/freezing point
- 68~95 ℃
- Initial boiling point and range
- 335.5 ℃(1013.25 hPa)
- Flash point
- 265 ℃
- Vapour pressure
- 0 hPa (20℃)
- Water solubility
- 596 g/ℓ (20℃, pH: 10)
- Vapour density
- 1.44 g/㎤ (20℃)
- Relative density
- 1.44
- n-Octanol/water partition coefficient (Kow)
- -1.16 (log Pow, 25℃)
- Molecular weight
- 86.1
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 17 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Film former5
- Fragrance4
- Degradant/impurity (EPA)3
- Wrinkle resisting agent2
- Solvent1
- Deodorizer1
- Intermediate1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Fabrication of liquid antibacterial wound dressing with flexible mechanical properties based on polyvinyl alcohol/xanthan gum · 2025
- GC-MS Analysis of Antlions (Myrmeleon formicarius L.) Ethanol Extract with The Potential to Reduce Staphylococcus aureus Infection Causes Diabetic Ulcers Infection · 2024
- Anxiety caused by chronic exposure to methylisothiazolinone in zebrafish: behavioral analysis, brain histology and gene responses. · 2024
- Regeneration of collagen fibrils at the papillary dermis by reconstructing basement membrane at the dermal–epidermal junction · 2021
- 1‐(2‐Hydroxyethyl)‐2‐imidazolidinone, a heparanase and matrix metalloproteinase inhibitor, improves epidermal basement membrane structure and epidermal barrier function · 2019
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese