1H-indene is an ortho-fused bicyclic arene comprising of benzene and cyclopentene rings.
Definition
1H-indene is an ortho-fused bicyclic arene comprising of benzene and cyclopentene rings. It is an ortho-fused bicyclic arene and an indene.
Source: PubChem
US FDA substance register · UNII 67H8Y6LB8A · registered name INDENE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 95-13-6
- EC No.EU chemical inventory number
- 202-393-6
- DTXSIDUS EPA chemical ID
- DTXSID8042052
- DTXCIDUS EPA compound ID
- DTXCID6022052
- IUPAC
- 1H-Indene
- Molecular formula
- C9H8
- Molecular weight
- 116.163 g/mol
Measured properties
- Appearance
- liquid
- Colour
- colourless
- Melting/freezing point
- -1.8 ℃
- Initial boiling point and range
- 181.6 ℃
- Flash point
- 51 ℃
- Vapour pressure
- 1.19 ㎜Hg(25℃)
- Water solubility
- 0.0332 g/100㎖(25℃ (est.))
- Vapour density
- 4
- Relative density
- 0.9968 (20℃)
- n-Octanol/water partition coefficient (Kow)
- 2.92
- Auto-ignition temperature
- (4.13X10+7)
- Molecular weight
- 116.15
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance3
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Classification not possible
Skin Sensitization · Screening - Not classified
Skin Irritation · Screening - Classification not possible
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Overlooked Photochemical Risk of Antimicrobial Fragrances: Formation of Potent Allergens and Their Mechanistic Pathways · 2025
- BF 3 .OEt 2 ‐Catalyzed Regioselective One‐Pot Multicomponent Synthesis of Arylated 1 H ‐Indenes With EGFR Inhibitory Potential: A Combined Synthetic and Biocomputational Study · 2025
- Synthesis, Anticancer Activity, and Computational Studies of Novel Imidazo[1′,2′:1,5]pyrazolo[3,4‐b]pyridine Derivatives · 2025
- Ethyl Acetate Extract of Marine Algae, Halymenia durvillei, Provides Photoprotection against UV-Exposure in L929 and HaCaT Cells · 2022
- RIFM fragrance ingredient safety assessment, pyridine, 4-ethenyl-, reaction products with 3a,4,7,7a-tetrahydrodimethyl-4,7-methano-1H-indene, CAS Registry Number 125352-06-9. · 2020
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese