Ingredient Dictionary

IODINE

Diiodine is molecule comprising two covalently bonded iodine atoms with overall zero charge..

Definition

Diiodine is molecule comprising two covalently bonded iodine atoms with overall zero charge.. It has a role as a nutrient.

Source: PubChem

US FDA substance register · UNII 9679TC07X4 · registered name Iodine · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Iodine is the mineral that conforms to the formula:

Cosmetic roles

Inhibits microbial growthANTIMICROBIAL

Safety & regulatory references

Banned: Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea · United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · Health Canada Cosmetic Ingredient Hotlist · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex II (prohibited substances), entry 213

Source: EU prohibited substances (Annex II)

Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics

Source: Health Canada Cosmetic Ingredient Hotlist

Restriction II/213

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

IODINEINCI요오드Korean label name (MFDS standard)

CAS No.chemical registry number: 7553-56-2
EC No.EU chemical inventory number: 231-442-4
DTXSIDUS EPA chemical ID: DTXSID7034672
DTXCIDUS EPA compound ID: DTXCID5014672

IUPAC: Diiodine
Molecular formula: I2
Molecular weight: 253.80894 g/mol

Measured properties

Appearance: solid
Melting/freezing point: 113.6 ℃
Initial boiling point and range: 184.4 ℃
Vapour pressure: 31.1 ㎩(25℃)
Water solubility: 330 ㎎/ℓ(at 25°C)
Vapour density: 6.75 (185℃)
Relative density: 4.93
n-Octanol/water partition coefficient (Kow): 2.49
Viscosity: 2.27 cP(116℃)
Molecular weight: 253.8

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Intermediate2
Soil amendments2
Biocide1
pH regulating agent1
Processing aids not otherwise specified1
Plating agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

7 skin studies and 3 eye studies are on record.

Classed as highly irritating1Classed as moderate1Classed as low1

The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 10 studies

Severe Irritation
skin corrosion: in vitro / ex vivo · Screening · other guideline: EU B.46 (In vitro skin irritation: Reconstructed Human Epidermis (RhE) Test Method) according to
Category 6.5B (Category 1)
Skin Sensitization · Read Across
Category 6.3A (Category 2)
Skin Irritation · Read Across
Category 8.2C (Category 1C)
Skin Irritation · Read Across
Category 2
Skin Irritation · Screening
Category 1
Skin Sensitization · Screening
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Category 8.3A (Category 1)
Eye Irritation · Read Across
Category 2
Eye Irritation · Screening