Iodoform is a member of iodomethanes.
Definition
Iodoform is a member of iodomethanes.
Source: PubChem
US FDA substance register · UNII KXI2J76489 · registered name IODOFORM · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 75-47-8
- EC No.EU chemical inventory number
- 200-874-5
- DTXSIDUS EPA chemical ID
- DTXSID4020743
- DTXCIDUS EPA compound ID
- DTXCID40743
- IUPAC
- Triiodomethane
- Molecular formula
- CHI3
- Molecular weight
- 393.732 g/mol
Measured properties
- Appearance
- Iodoform appears as bright yellow or yellow powder or crystals. Penetrating odor. Unctuous feel. Odor threshold 0.4 ppb. (NTP, 1992) · Yellow to greenish-yellow powder or crystalline solid with a pungent, disagreeable odor. [antiseptic for external use], [NIOSH]
- Odour
- Characteristic, disagreeable odor
- Boiling point
- 424 °F at 760 mmHg (Sublimes) (NTP, 1992) · 218
- Melting point
- 248 °F (NTP, 1992) · 119-122
- Solubility
- less than 1 mg/mL at 75 °F (NTP, 1992) · Slightly soluble
- Density
- 4.008 at 68 °F (NTP, 1992) - Denser than water, will sink · Specific Gravity: 4.008 g/cu cm @ 25 °C
- Odour threshold
- 5
- Melting/freezing point
- 119 ℃
- Initial boiling point and range
- 218 ℃
- Vapour pressure
- 0.0396 ㎜Hg (25℃, est.)
- Vapour density
- 4.008 g/㎤ (25℃)
- Relative density
- 4.008 (25℃)
- n-Octanol/water partition coefficient (Kow)
- 3.03 (est.)
- Decomposition temperature
- 204 ℃ (161.9kg cal/g at 20℃)
- Molecular weight
- 393.73
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance1
- Biocide1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- Classification not possible
Skin Sensitization · Screening - Category 6.3A (Category 2)
Skin Irritation · Read Across - Classification not possible
Skin Irritation · Screening - Category 2A-2B
Eye Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Allergic reaction after iodoform-containing intracanal medication application following an endodontic root canal therapy · 2025
- SETTING OF PARAMETERS OF ACUTE AND SUBACUTE TOXICITY OF THE POWDER BASED ON IODOFORM · 2021
- Bismuth Iodoform Paraffin Paste [bipp] Wick versus Topical Levofloxacin Drops in Rapid Drying of Wet Ear in Tubotympainic Chronic Suppurative Otitis Media · 2017
- Tissue inflammatory response to implantation of calcium hydroxide and iodoform in the back of rats · 2010
- Re: The need to include BIPP reactions in routine consent: we should not be patching together patch tests for bismuth iodoform paraffin paste allergy · 2008
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese