IODOPROPYNYL BUTYLCARBAMATE
製品には実際どれくらい入っているか
この成分の含有量を表示した製品はまだありません。
この成分を含む製品のうち4件は全成分の前の方(1%ラインより前)、52件は後ろ(ふつう1%以下)に書いています。
この成分を含む製品
確認済み 56件中 12件 · 十分に入っている製品から · 全 56件を見る
Curl JunkieCurl Junkie CURLS IN A BOTTLE! HAIR STYLING SOLUTION
Curl JunkieCurl Junkie SMOOTHING LOTION LEAVE-IN
O'Keeffe'sHealthy Feet Foot Cream Tube 85g
OuidadOuidad Curl Quencher® Hydrafusion® Intense Curl Cream
Miss Jessie'sMiss Jessie's Coily Custard - Curl Refresher
EltaMDEltaMD UV Clear Broad Spectrum SPF 46
Curl JunkieCurl Junkie PATTERN PUSHA - HAIR STYLING GEL
CurlsmithCurlsmith Fragrance-Free Strong Hold Gel
EltaMDEltaMD UV Clear Tinted Broad Spectrum SPF 46
EltaMDEltaMD UV Daily Limited Edition Bottle Broad Spectrum SPF 40
EltaMDEltaMD UV Sport Broad Spectrum SPF 50+
CurlsmithCurlsmith Hair Makeup - Copper
定義
Iodopropynyl Butylcarbamate is the organic compound that conforms to the formula:
米国FDA 物質登録 · UNII 603P14DHEB · 登録名 Iodocarb · 単一の化学物質
3-iodoprop-2-yn-1-yl butylcarbamate is a carbamate ester that is carbamic acid in which the nitrogen has been substituted by a butyl group and in which the hydrogen of the carboxy group is replaced by a 1-iodoprop-2-yn-3-yl group. A fungicide, it is used as a preservative and sapstain control chemical in wood products and as a preservative in adhesives, paints, latex paper coating, plastic, water-based inks, metal working fluids, textiles, and numerous consumer products. It has a role as a xenobiotic, an environmental contaminant and an antifungal agrochemical. It is a carbamate ester, an organoiodine compound, an acetylenic compound and a carbamate fungicide.
出典: PubChem
化粧品での役割
安全性・規制情報
- 制限
- 韓国
- 許可された防腐剤
- イギリス
出典: 韓国食薬処 化粧品規制情報 · ASEAN 化粧品指令 · EU 化粧品規則 · 日本 化粧品基準 · 台湾FDA 化粧品成分 · 英国 化粧品規則
アルゼンチン · ブラジル
- Maximum concentration permitted at final product : a) 0.02% in rinse-off products b) 0.01% in products not RINSING to n, except in deodorants / antiperspirants c) 0.0075%. Deodorants / Antiperspirants
- Other limitations and requirements : No use in products for oral hygiene and lip. a) No use in products for children under 3 years, except in bath products, shower gel and shampoo. b) No use in lotions and body creams that are applied in large extensions body; No use in products for children under 3 years of age. c) No use in lotions and body creams that are applied in large body extensions. No use in products for children.
- Use conditions and warnings that must appear on the label : a) For products use Adults: "Do not use in children" For products aimed at children: "Do not use in children under three years of age" (This warning does not apply to bath products, shower gel and shampoo). b) For products use Adult: "Do not use in children" For products aimed at children: "Do not use in children under three years of age" c) Do not use in children
ASEAN
- Maximum authorised concentration in the finished cosmetic product : (a) rinse-off products: 0.02 % (b) leave-on products: 0.01 % except in deodorants & antiperspirants: 0.0075 %
- Other limitations and requirements : Not to be used in oral hygiene and lip care products (a) Not to be used in preparations for children under three years of age, except in bath products/shower gels and shampoos. (b) Not to be used in body lotion and body cream (Concerns any products aimed to be applied on a large part of the body) Not to be used in preparations for children under three years of age.
- Conditions of use and warning which must be printed on the labels : (a) Not to be used for children under three years of age (Solely for products, other than bath products/shower gels and shampoo, which might be used for children under three years of age.) (b) Not to be used for children under three years of age (Solely for products which might be used for children under three years of age)
台湾
- ※ 未列於本表中之防腐劑成分,倘歐、美、日三國家地區政府已公告准用且有其限量管制規定者,我國亦依其限用標準准予使用。
- 倘前述三國家地區政府管理有差異時,則採其中限量規定方式最安全者。
- ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
- 用途 : 防腐
- 最大配合量 : (a) 立即沖洗產品 : 0.02%
- 不得使用於口腔與唇部製劑。不得使用於三歲以下孩童之產品,但沐浴和洗髮產品除外。
- (b) 非立即沖洗產品 : 0.01%
- 不得使用於身體乳液和身體乳霜產品。
- (c) 止汗劑及制臭劑 : 0.0075%
- (b)&(c) 不得使用於三歲以下孩童之產品。
- (b)&(c) 不得使用於三歲以下孩童之產品
- (b)&(c):不得使用於三歲以下孩童。
日本
- 100gあたりの最大配合量 (Cosmetics not used for mucosa and to be washed away) : 0.02 g
- 100gあたりの最大配合量 (Cosmetics not used for mucosa and not to be washed away) : 0.02 g
- 100gあたりの最大配合量 (Cosmetics that may be used for mucosa) : 0.02 g
中国
- 最大配合量 : (a) 0.02%
- (b) 0.01%
- (c) 0.0075%
欧州連合
- Product Type, body parts : a) Rinse-off products b) Leave-on products c) Deodorants/antiperspirants
- Maximum concentration in ready for use preparation : a) 0.02% b) 0.01% c) 0.0075%
- Other : Not to be used in oral and lip products a) Not to be used in products for children under 3 years of age, except in bath products / shower gels and shampoos b) Not to be used in body lotion and body cream (13) b) and c) Not to be used in products for children under 3 years of age
- Wording of conditions of use and warnings : a) Not to be used for children under three years of age (11) b) and c) Not to be used for children under three years of age (12)
出典: 韓国食薬処 化粧品規制情報
韓国の有害物質GHS分類なし · 既存化学物質
EU化粧品規則 附属書V(許可防腐剤) 第56項 · 最大濃度 a) 0.02% b) 0.01% c) 0.0075% · 適用 a) Rinse-off products b) Leave-on products c) Deodorants/antiperspirants
出典: EU 許可防腐剤(附属書V)
Restriction V/56 · Other restriction: ban substances that deplete the ozone layer
出典: EU CosIng 成分リスト
Reviewed by CIR: 40th Anniversary Overview and Rereview Summaries From 2011 to 2015
出典: 米国CIR 安全性評価
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
公式表示名・定義
日本化粧品工業会の表示名称 ブチルカルバミン酸ヨウ化プロピニル: 本品は、次の化学式で表されるカルバミン酸エステル誘導体である。
出典: 日本化粧品工業会 表示名称
別名・識別情報
- CAS No.化学物質登録番号
- 55406-53-6
- EC No.EU化学物質目録番号
- 259-627-5
- DTXSID米国EPA化学物質番号
- DTXSID0028038
- DTXCID米国EPA化合物番号
- DTXCID908038
- IUPAC
- 3-Iodoprop-2-yn-1-yl butylcarbamate
- 分子式
- C8H12INO2
- 分子量
- 281.093 g/mol
測定された物性
- 性状
- 3-iodo-2-propynyl butylcarbamate is an off-white solid. · White solid with a pungent odor, [HSDB]
- 臭い
- Sharp pungent odor
- 融点
- 66 °C
- 溶解性
- In water, 156 mg/L at 20 °C
- 密度
- 1.575 g/mL · 1.575 @25 °C
- 色
- 灰色
- 臭いの閾値
- 156 ppm (156ppm at 20C)
- 融点・凝固点
- 66 ℃
- 蒸気圧
- 0.0000525 ㎜Hg
- 溶解度
- 156 ㎎/ℓ (at 20℃)
- 比重
- 1.575
- n-オクタノール/水分配係数(Kow)
- 2.4
- 分子量
- 281
物質そのものを測定した値です。安全保健公団(KOSHA)の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。
出典: PubChem · 韓国安全保健公団 SDS
製品が実際に使っている用途
米国EPAにこの成分を届け出た製品87件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。
- Preservative42
- Biocide37
- Processing aids not otherwise specified8
出典: 米国EPA CompTox
刺激・感作試験の記録
皮膚試験9件・眼試験4件の記録があります。
試験の結論はおおむね一致しています(100%)。 原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。
試験13件をすべて見る
- Skin irritation - category 2
Skin Irritation · Screening - Sh
Skin Sensitization · Authoritative - Skin Sens. 1
Skin Sensitization · Authoritative - Skin sensitisation - category 1
Skin Sensitization · Screening - Category 6.3B (Category 3)
Skin Irritation · Read Across - Category 6.5B (Category 1)
Skin Sensitization · Read Across - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) 1992 according to EPA OPPTS 870.2600 (Skin Sensitisation) 1998 according to EU Method B.6 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EPA OPP 81-5 (Acute Dermal Irritation) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to EPA OPP 81-6 (Skin Sensitisation) 1987 according to OECD Guideline 406 (Skin Sensitisation) 1992 - Eye damage - category 1
Eye Irritation · Screening - Eye Dam. 1
Eye Irritation · Authoritative - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · EPA OPP 81-4 (Acute Eye Irritation) according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across
出典: 米国EPA CompTox
関連文献
- [Anal and palmar contact dermatitis caused by iodopropynyl butylcarbamate in moist sanitary wipes]. · 2003
- PLASMA CELL GINGIVITIS DUE TO COSMETICS RELATED IODOPROPYNYL BUTYLCARBAMATE (IPBC) ALLERGY IN A TEENAGE FEMALE PATIENT MASKING AS DESQUAMATIVE GINGIVITIS. · 2019
- Suspected allergic contact dermatitis to iodopropynyl butylcarbamate in an alcohol hand rub commonly used in Australian health‐care settings · 2014
- Iodopropynylbutyl carbamate 0·2% is suggested for patch testing of patients with eczema possibly related to preservatives · 2004
- The sensitizing potential of iodopropynyl butylcarbamate in the local lymph node assay · 2004
連携データベース 28
- ASEAN 化粧品指令
- ChEBI
- ChEMBL
- EU CosIng 成分リスト 2
- EU SCCS 安全性意見
- EU 化粧品規則
- EU 許可防腐剤(附属書V)
- PubChem 2
- Tlooto 学術文献検索 2 3 4 5
- UniChem 化学物質統合ID
- Wikidata
- Wikipedia · 英語
- オーストラリア 化学物質リスト(AICIS)
- 英国 化粧品規則
- 韓国 有害物質GHS情報(環境公団)
- 韓国安全保健公団 SDS
- 韓国食薬処 化粧品規制情報 2 3 4
- 韓国食薬処 化粧品原料成分 2
- 台湾FDA 化粧品成分
- 大韓化粧品協会 成分辞典
- 中国 既存化粧品原料リスト(IECIC)
- 日本 化粧品基準
- 日本化粧品工業会 表示名称
- 米国CIR 安全性評価 2 3
- 米国EPA CompTox 2
- 米国EPA 化学物質DB(DSSTox)
- 米国FDA 物質識別番号(UNII)
- 米国FDA 物質登録(GSRS)