How much products actually contain
No product states its amount yet.
Of the products containing it, 4 list it before the 1% line and 52 after it (usually 1% or less).
Products using this ingredient
12 of 56 confirmed · likeliest to carry enough first · See all 56
Curl JunkieCurl Junkie CURLS IN A BOTTLE! HAIR STYLING SOLUTION
Curl JunkieCurl Junkie SMOOTHING LOTION LEAVE-IN
O'Keeffe'sHealthy Feet Foot Cream Tube 85g
OuidadOuidad Curl Quencher® Hydrafusion® Intense Curl Cream
Miss Jessie'sMiss Jessie's Coily Custard - Curl Refresher
EltaMDEltaMD UV Clear Broad Spectrum SPF 46
Curl JunkieCurl Junkie PATTERN PUSHA - HAIR STYLING GEL
CurlsmithCurlsmith Fragrance-Free Strong Hold Gel
EltaMDEltaMD UV Clear Tinted Broad Spectrum SPF 46
EltaMDEltaMD UV Daily Limited Edition Bottle Broad Spectrum SPF 40
EltaMDEltaMD UV Sport Broad Spectrum SPF 50+
CurlsmithCurlsmith Hair Makeup - Copper
Definition
Iodopropynyl Butylcarbamate is the organic compound that conforms to the formula:
US FDA substance register · UNII 603P14DHEB · registered name Iodocarb · single chemical substance
3-iodoprop-2-yn-1-yl butylcarbamate is a carbamate ester that is carbamic acid in which the nitrogen has been substituted by a butyl group and in which the hydrogen of the carboxy group is replaced by a 1-iodoprop-2-yn-3-yl group. A fungicide, it is used as a preservative and sapstain control chemical in wood products and as a preservative in adhesives, paints, latex paper coating, plastic, water-based inks, metal working fluids, textiles, and numerous consumer products. It has a role as a xenobiotic, an environmental contaminant and an antifungal agrochemical. It is a carbamate ester, an organoiodine compound, an acetylenic compound and a carbamate fungicide.
Source: PubChem
Cosmetic roles
Safety & regulatory references
- Restricted
- South Korea · Taiwan
- Allowed preservative
- Taiwan · United Kingdom
Source: MFDS (Korea) cosmetic regulatory information · ASEAN Cosmetic Directive · EU Cosmetics Regulation · Japan Standards for Cosmetics · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)
Argentina · Brazil
- Maximum concentration permitted at final product : a) 0.02% in rinse-off products b) 0.01% in products not RINSING to n, except in deodorants / antiperspirants c) 0.0075%. Deodorants / Antiperspirants
- Other limitations and requirements : No use in products for oral hygiene and lip. a) No use in products for children under 3 years, except in bath products, shower gel and shampoo. b) No use in lotions and body creams that are applied in large extensions body; No use in products for children under 3 years of age. c) No use in lotions and body creams that are applied in large body extensions. No use in products for children.
- Use conditions and warnings that must appear on the label : a) For products use Adults: "Do not use in children" For products aimed at children: "Do not use in children under three years of age" (This warning does not apply to bath products, shower gel and shampoo). b) For products use Adult: "Do not use in children" For products aimed at children: "Do not use in children under three years of age" c) Do not use in children
ASEAN
- Maximum authorised concentration in the finished cosmetic product : (a) rinse-off products: 0.02 % (b) leave-on products: 0.01 % except in deodorants & antiperspirants: 0.0075 %
- Other limitations and requirements : Not to be used in oral hygiene and lip care products (a) Not to be used in preparations for children under three years of age, except in bath products/shower gels and shampoos. (b) Not to be used in body lotion and body cream (Concerns any products aimed to be applied on a large part of the body) Not to be used in preparations for children under three years of age.
- Conditions of use and warning which must be printed on the labels : (a) Not to be used for children under three years of age (Solely for products, other than bath products/shower gels and shampoo, which might be used for children under three years of age.) (b) Not to be used for children under three years of age (Solely for products which might be used for children under three years of age)
Japan
- Maximum amount per 100 g (Cosmetics not used for mucosa and to be washed away) : 0.02 g
- Maximum amount per 100 g (Cosmetics not used for mucosa and not to be washed away) : 0.02 g
- Maximum amount per 100 g (Cosmetics that may be used for mucosa) : 0.02 g
China
- Maximum concentration : (a) 0.02%
- (b) 0.01%
- (c) 0.0075%
European Union
- Product Type, body parts : a) Rinse-off products b) Leave-on products c) Deodorants/antiperspirants
- Maximum concentration in ready for use preparation : a) 0.02% b) 0.01% c) 0.0075%
- Other : Not to be used in oral and lip products a) Not to be used in products for children under 3 years of age, except in bath products / shower gels and shampoos b) Not to be used in body lotion and body cream (13) b) and c) Not to be used in products for children under 3 years of age
- Wording of conditions of use and warnings : a) Not to be used for children under three years of age (11) b) and c) Not to be used for children under three years of age (12)
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
EU Cosmetics Regulation, Annex V (allowed preservatives), entry 56 · maximum concentration a) 0.02% b) 0.01% c) 0.0075% · applies to a) Rinse-off products b) Leave-on products c) Deodorants/antiperspirants
Restriction V/56 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: 40th Anniversary Overview and Rereview Summaries From 2011 to 2015
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ブチルカルバミン酸ヨウ化プロピニル: 本品は、次の化学式で表されるカルバミン酸エステル誘導体である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 55406-53-6
- EC No.EU chemical inventory number
- 259-627-5
- DTXSIDUS EPA chemical ID
- DTXSID0028038
- DTXCIDUS EPA compound ID
- DTXCID908038
- IUPAC
- 3-Iodoprop-2-yn-1-yl butylcarbamate
- Molecular formula
- C8H12INO2
- Molecular weight
- 281.093 g/mol
Measured properties
- Appearance
- 3-iodo-2-propynyl butylcarbamate is an off-white solid. · White solid with a pungent odor, [HSDB]
- Odour
- Sharp pungent odor
- Melting point
- 66 °C
- Solubility
- In water, 156 mg/L at 20 °C
- Density
- 1.575 g/mL · 1.575 @25 °C
- Colour
- grey
- Odour threshold
- 156 ppm (156ppm at 20C)
- Melting/freezing point
- 66 ℃
- Vapour pressure
- 0.0000525 ㎜Hg
- Water solubility
- 156 ㎎/ℓ (at 20℃)
- Relative density
- 1.575
- n-Octanol/water partition coefficient (Kow)
- 2.4
- Molecular weight
- 281
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 87 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Preservative42
- Biocide37
- Processing aids not otherwise specified8
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
9 skin studies and 4 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 13 studies
- Skin irritation - category 2
Skin Irritation · Screening - Sh
Skin Sensitization · Authoritative - Skin Sens. 1
Skin Sensitization · Authoritative - Skin sensitisation - category 1
Skin Sensitization · Screening - Category 6.3B (Category 3)
Skin Irritation · Read Across - Category 6.5B (Category 1)
Skin Sensitization · Read Across - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) 1992 according to EPA OPPTS 870.2600 (Skin Sensitisation) 1998 according to EU Method B.6 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EPA OPP 81-5 (Acute Dermal Irritation) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to EPA OPP 81-6 (Skin Sensitisation) 1987 according to OECD Guideline 406 (Skin Sensitisation) 1992 - Eye damage - category 1
Eye Irritation · Screening - Eye Dam. 1
Eye Irritation · Authoritative - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · EPA OPP 81-4 (Acute Eye Irritation) according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- [Anal and palmar contact dermatitis caused by iodopropynyl butylcarbamate in moist sanitary wipes]. · 2003
- PLASMA CELL GINGIVITIS DUE TO COSMETICS RELATED IODOPROPYNYL BUTYLCARBAMATE (IPBC) ALLERGY IN A TEENAGE FEMALE PATIENT MASKING AS DESQUAMATIVE GINGIVITIS. · 2019
- Suspected allergic contact dermatitis to iodopropynyl butylcarbamate in an alcohol hand rub commonly used in Australian health‐care settings · 2014
- Iodopropynylbutyl carbamate 0·2% is suggested for patch testing of patients with eczema possibly related to preservatives · 2004
- The sensitizing potential of iodopropynyl butylcarbamate in the local lymph node assay · 2004
Linked databases 28
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU allowed preservatives (Annex V)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU SCCS safety opinions
- Japan Standards for Cosmetics
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3 4
- PubChem 2
- Taiwan FDA cosmetic ingredients
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English