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成分词典

成分词典

IODOPROPYNYL BUTYLCARBAMATE

分子结构

产品中实际含有多少

暂无产品标示该成分含量。

含该成分的产品中,4 款将其列在 1% 线之前,52 款列在之后(通常不超过 1%)。

含有此成分的产品

已确认 56 款中的 12 款 · 按含量充足程度排序 · 查看全部 56 款

定义

Iodopropynyl Butylcarbamate is the organic compound that conforms to the formula:

美国FDA 物质登记 · UNII 603P14DHEB · 登记名称 Iodocarb · 单一化学物质

来源: 美国FDA 物质识别码(UNII)

3-iodoprop-2-yn-1-yl butylcarbamate is a carbamate ester that is carbamic acid in which the nitrogen has been substituted by a butyl group and in which the hydrogen of the carboxy group is replaced by a 1-iodoprop-2-yn-3-yl group. A fungicide, it is used as a preservative and sapstain control chemical in wood products and as a preservative in adhesives, paints, latex paper coating, plastic, water-based inks, metal working fluids, textiles, and numerous consumer products. It has a role as a xenobiotic, an environmental contaminant and an antifungal agrochemical. It is a carbamate ester, an organoiodine compound, an acetylenic compound and a carbamate fungicide.

来源: PubChem

化妆品中的作用

防止产品中微生物滋生PRESERVATIVE

安全与法规参考

限用
韩国
准用防腐剂
英国

来源: 韩国食药处 化妆品法规信息 · 东盟化妆品指令 · 欧盟化妆品法规 · 日本化妆品标准 · 台湾FDA 化妆品成分 · 英国化妆品法规

阿根廷 · 巴西

  • Maximum concentration permitted at final product : a) 0.02% in rinse-off products b) 0.01% in products not RINSING to n, except in deodorants / antiperspirants c) 0.0075%. Deodorants / Antiperspirants
  • Other limitations and requirements : No use in products for oral hygiene and lip. a) No use in products for children under 3 years, except in bath products, shower gel and shampoo. b) No use in lotions and body creams that are applied in large extensions body; No use in products for children under 3 years of age. c) No use in lotions and body creams that are applied in large body extensions. No use in products for children.
  • Use conditions and warnings that must appear on the label : a) For products use Adults: "Do not use in children" For products aimed at children: "Do not use in children under three years of age" (This warning does not apply to bath products, shower gel and shampoo). b) For products use Adult: "Do not use in children" For products aimed at children: "Do not use in children under three years of age" c) Do not use in children

东盟

  • Maximum authorised concentration in the finished cosmetic product : (a) rinse-off products: 0.02 % (b) leave-on products: 0.01 % except in deodorants & antiperspirants: 0.0075 %
  • Other limitations and requirements : Not to be used in oral hygiene and lip care products (a) Not to be used in preparations for children under three years of age, except in bath products/shower gels and shampoos. (b) Not to be used in body lotion and body cream (Concerns any products aimed to be applied on a large part of the body) Not to be used in preparations for children under three years of age.
  • Conditions of use and warning which must be printed on the labels : (a) Not to be used for children under three years of age (Solely for products, other than bath products/shower gels and shampoo, which might be used for children under three years of age.) (b) Not to be used for children under three years of age (Solely for products which might be used for children under three years of age)

台湾

  • ※ 未列於本表中之防腐劑成分,倘歐、美、日三國家地區政府已公告准用且有其限量管制規定者,我國亦依其限用標準准予使用。
  • 倘前述三國家地區政府管理有差異時,則採其中限量規定方式最安全者。
  • ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
  • 用途 : 防腐
  • 最大配合量 : (a) 立即沖洗產品 : 0.02%
  • 不得使用於口腔與唇部製劑。不得使用於三歲以下孩童之產品,但沐浴和洗髮產品除外。
  • (b) 非立即沖洗產品 : 0.01%
  • 不得使用於身體乳液和身體乳霜產品。
  • (c) 止汗劑及制臭劑 : 0.0075%
  • (b)&(c) 不得使用於三歲以下孩童之產品。
  • (b)&(c) 不得使用於三歲以下孩童之產品
  • (b)&(c):不得使用於三歲以下孩童。

日本

  • 每100g最大配合量 (Cosmetics not used for mucosa and to be washed away) : 0.02 g
  • 每100g最大配合量 (Cosmetics not used for mucosa and not to be washed away) : 0.02 g
  • 每100g最大配合量 (Cosmetics that may be used for mucosa) : 0.02 g

中国

  • 最大配合量 : (a) 0.02%
  • (b) 0.01%
  • (c) 0.0075%

欧盟

  • Product Type, body parts : a) Rinse-off products b) Leave-on products c) Deodorants/antiperspirants
  • Maximum concentration in ready for use preparation : a) 0.02% b) 0.01% c) 0.0075%
  • Other : Not to be used in oral and lip products a) Not to be used in products for children under 3 years of age, except in bath products / shower gels and shampoos b) Not to be used in body lotion and body cream (13) b) and c) Not to be used in products for children under 3 years of age
  • Wording of conditions of use and warnings : a) Not to be used for children under three years of age (11) b) and c) Not to be used for children under three years of age (12)

来源: 韩国食药处 化妆品法规信息

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息(环境公团)

欧盟化妆品法规 附录V(准用防腐剂) 第56项 · 最高浓度 a) 0.02% b) 0.01% c) 0.0075% · 适用 a) Rinse-off products b) Leave-on products c) Deodorants/antiperspirants

来源: 欧盟准用防腐剂(附录V)

Restriction V/56 · Other restriction: ban substances that deplete the ozone layer

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: 40th Anniversary Overview and Rereview Summaries From 2011 to 2015

来源: 美国CIR 安全性评估

详细资料——标示名称、识别编号、物性、试验记录、文献

官方标示名称和定义

日本化妆品工业联合会标示名称 ブチルカルバミン酸ヨウ化プロピニル: 本品は、次の化学式で表されるカルバミン酸エステル誘導体である。

来源: 日本化妆品工业联合会标示名称

别名和识别信息

IODOPROPYNYL BUTYLCARBAMATEINCI아이오도프로피닐부틸카바메이트韩国标示名称(食药处标准名)Carbamic acid, butyl-, 3-iodo-2-propynyl ester同义名ブチルカルバミン酸ヨウ化プロピニル日本标示名称
CAS No.化学物质登记号
55406-53-6
EC No.欧盟化学品目录编号
259-627-5
DTXSID美国EPA化学品编号
DTXSID0028038
DTXCID美国EPA化合物编号
DTXCID908038
IUPAC
3-Iodoprop-2-yn-1-yl butylcarbamate
分子式
C8H12INO2
分子量
281.093 g/mol

实测物性

性状
3-iodo-2-propynyl butylcarbamate is an off-white solid. · White solid with a pungent odor, [HSDB]
气味
Sharp pungent odor
熔点
66 °C
溶解性
In water, 156 mg/L at 20 °C
密度
1.575 g/mL · 1.575 @25 °C
颜色
灰色
嗅觉阈值
156 ppm (156ppm at 20C)
熔点/凝固点
66 ℃
蒸气压
0.0000525 ㎜Hg
溶解度
156 ㎎/ℓ (at 20℃)
比重
1.575
正辛醇/水分配系数(Kow)
2.4
分子量
281

这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。

来源: PubChem · 韩国安全保健公团 安全数据表

产品实际使用的用途

这是向美国 EPA 申报含该成分的 87 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。

  • Preservative42
  • Biocide37
  • Processing aids not otherwise specified8

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 9 项、眼部试验 4 项。

归类为中等1 项

试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。

查看全部 13 项试验
  • Skin irritation - category 2
    Skin Irritation · Screening
  • Sh
    Skin Sensitization · Authoritative
  • Skin Sens. 1
    Skin Sensitization · Authoritative
  • Skin sensitisation - category 1
    Skin Sensitization · Screening
  • Category 6.3B (Category 3)
    Skin Irritation · Read Across
  • Category 6.5B (Category 1)
    Skin Sensitization · Read Across
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) 1992 according to EPA OPPTS 870.2600 (Skin Sensitisation) 1998 according to EU Method B.6 (Skin Sensitisation)
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · EPA OPP 81-5 (Acute Dermal Irritation) according to
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to EPA OPP 81-6 (Skin Sensitisation) 1987 according to OECD Guideline 406 (Skin Sensitisation) 1992
  • Eye damage - category 1
    Eye Irritation · Screening
  • Eye Dam. 1
    Eye Irritation · Authoritative
  • Corrosive or Irritation Persists for > 21 days
    eye irritation: in vivo · Screening · EPA OPP 81-4 (Acute Eye Irritation) according to
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across

来源: 美国EPA CompTox

相关文献

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