Ingredient Dictionary

ISOAMYL SALICYLATE

Isoamyl salicylate is a member of phenols and a benzoate ester.

Definition

Isoamyl salicylate is a member of phenols and a benzoate ester. It is functionally related to a salicylic acid.

Source: PubChem

US FDA substance register · UNII M25E4ZMR0N · registered name ISOAMYL SALICYLATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

ISOAMYL SALICYLATEINCI아이소아밀살리실레이트Korean label name (MFDS standard)Benzoic acid, 2-hydroxy-, 3-methylbutyl esterSynonym

CAS No.chemical registry number: 87-20-7
EC No.EU chemical inventory number: 201-730-4
DTXSIDUS EPA chemical ID: DTXSID9041655
DTXCIDUS EPA compound ID: DTXCID7021655

IUPAC: 3-Methylbutyl 2-hydroxybenzoate
Molecular formula: C12H16O3
Molecular weight: 208.257 g/mol

Measured properties

Appearance: liquid
Melting/freezing point: 5.4 ℃
Initial boiling point and range: 276~277 ℃
Flash point: 137 ℃
Vapour pressure: 0.08 hPa(20 deg C)
Water solubility: 6.3 ㎎/ℓ((20℃))
Relative density: 1.05 (20 °C)
n-Octanol/water partition coefficient (Kow): 4.78 (23℃)
Auto-ignition temperature: 395 ℃
Molecular weight: 208.26

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 41 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance36
Flavouring and nutrient3
Deodorizer2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 0 eye studies are on record.

Classed as highly irritating1Classed as low1

The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
SkinIrr2
Skin Irritation · QSAR Predicted