Ingredient Dictionary

ISOBUTYL ACETATE

Isobutyl acetate is the acetate ester of isobutanol.

How much products actually contain

No product states its amount yet.

Of the products containing it, 7 list it before the 1% line and 2 after it (usually 1% or less).

Products using this ingredient

9 of 9 confirmed · likeliest to carry enough first

Definition

Isobutyl acetate is the acetate ester of isobutanol. It has a role as a Saccharomyces cerevisiae metabolite. It is functionally related to an isobutanol.

Source: PubChem

US FDA substance register · UNII 7CR47FO6LF · registered name ISOBUTYL ACETATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Base that dissolves other ingredientsSOLVENTGives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Final Report of the Cosmetic Ingredient Reveiw Expert Panel on the Safety Assessment of Methyl Acetate

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name 酢酸イソブチル: 本品は、酢酸（＊）とイソブチルアルコールのエステルであり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

ISOBUTYL ACETATEINCI아이소부틸아세테이트Korean label name (MFDS standard)Acetic acid, 2-methylpropyl esterSynonym酢酸イソブチルJapanese labelling name

CAS No.chemical registry number: 110-19-0
EC No.EU chemical inventory number: 203-745-1
DTXSIDUS EPA chemical ID: DTXSID5026837
DTXCIDUS EPA compound ID: DTXCID906837

IUPAC: 2-Methylpropyl acetate
Molecular formula: C6H12O2
Molecular weight: 116.16 g/mol

Measured properties

Appearance: Isobutyl acetate appears as a clear colorless liquid with a fruity odor. Flash point 64 °F. Less dense than water (6.2 lb / gal) and insoluble in water. Vapors are heavier than air. · Liquid
Odour: Fruit-like odor · Fruity, floral odor
Boiling point: 243.1 °F at 760 mmHg (USCG, 1999) · 116.5 °C
Melting point: -142.8 °F (USCG, 1999) · -98.8 °C
Solubility: 0.6 % at 77 °F (NIOSH, 2024) · Miscible with ethanol, ether and methanol, soluble in acetone, slightly soluble in carbon tetrachloride
Density: 0.871 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.8712 g/cu cm at 20 °C
Colour: colourless
Melting/freezing point: -99 ℃( -98.85℃ 3))
Initial boiling point and range: 118 ℃
Flash point: 18 ℃(c.c.)
Upper/lower flammability or explosive limits: 10.5 / 1.3 %
Vapour pressure: 1.73 ㎪(20℃)
Water solubility: 0.67 g/100㎖(20℃)
Vapour density: 4
Relative density: 0.8712
n-Octanol/water partition coefficient (Kow): 1.6 ( = log Pow)
Auto-ignition temperature: 421 ℃
Viscosity: 0.8 ㎡/s(20℃)
Molecular weight: 116.16

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 26 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance11
Solvent11
Flavouring and nutrient2
Intermediate1
No specific technical function1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 2 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 6 studies

Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) adopted 1981
Classification not possible
Skin Sensitization · Screening
Classification not possible
Skin Irritation · Screening
Category 6.3B (Category 3)
Skin Irritation · Read Across
Category 2B
Eye Irritation · Screening
Category 6.4A (Category 2A)
Eye Irritation · Read Across