产品中实际含有多少
暂无产品标示该成分含量。
含该成分的产品中，0 款将其列在 1% 线之前，1 款列在之后（通常不超过 1%）。
含有此成分的产品
已确认 1 款中的 1 款 · 按含量充足程度排序
定义
美国FDA 物质登记 · UNII V11534UYZ0 · 登记名称 ISOBUTYL METHACRYLATE · 单一化学物质
化妆品中的作用
在涂抹处形成薄膜FILM FORMING
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
Other restriction: ban substances that deplete the ozone layer
来源: 欧盟 CosIng 成分清单
Reviewed by CIR: Methacrylate Ester Monomers
来源: 美国CIR 安全性评估
Reviewed by CIR: Final Report on the Safety Assessment of Methacrylate Ester Monomers Used in Nail Enhancement Products
来源: 美国CIR 安全性评估
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 メタクリル酸イソブチル: 本品は、次の化学式で表される有機化合物である。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
ISOBUTYL METHACRYLATEINCI아이소부틸메타크릴레이트韩国标示名称（食药处标准名）2-Propenoic acid, 2-methyl-, 2-methylpropyl ester同义名メタクリル酸イソブチル日本标示名称
- CAS No.化学物质登记号
- 97-86-9
- EC No.欧盟化学品目录编号
- 202-613-0
- DTXSID美国EPA化学品编号
- DTXSID3025461
- DTXCID美国EPA化合物编号
- DTXCID505461
- IUPAC
- 2-Methylpropyl 2-methylprop-2-enoate
- 分子式
- C8H14O2
- 分子量
- 142.198 g/mol
实测物性
- 性状
- Isobutyl methacrylate is a colorless liquid with a flash point of 120 °F. When heated to high temperatures it may release acrid smoke and fumes. If it is subjected to heat for prolonged periods or becomes contaminated, it is subject to polymerization. If the polymerization takes place inside a container, the container may violently rupture. The vapors are heavier than air. It may be irritating to · CBI, Liquid
- 沸点
- 311 °F at 760 mmHg (NTP, 1992) · 155 °C
- 熔点
- Freezing pt: -61 °C
- 溶解性
- Insoluble (<1mg/ml) (NTP, 1992) · Miscible with ethanol, ethyl ether
- 密度
- 0.8858 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.8858 g/cu cm at 20 °C
- 颜色
- 无色
- 熔点/凝固点
- -61 ℃
- 初沸点和沸程
- 155 ℃
- 闪点
- 49 ℃
- 蒸气压
- 3.63 ㎜Hg
- 溶解度
- 439 ㎎/ℓ
- 蒸气密度
- 4.91 (at 60℃)
- 比重
- 0.8858
- 正辛醇/水分配系数（Kow）
- 2.95
- 自燃温度
- 390 ℃
- 分子量
- 142.22
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 11 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Monomers3
- Intermediate3
- Adhesion/cohesion promoter2
- Flavouring and nutrient1
- Fragrance1
- Film former1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 11 项、眼部试验 7 项。
归类为中等2 项
试验结论基本一致（100%）。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 18 项试验
- Category 6.3B (Category 3)
Skin Irritation · Read Across - Severe Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act Regulations, Section 191.12, Federal Register: 29, 13009 (1964). according to - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Severe Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labelling Act Regulations, Section 191.11, published in the Federal Register (USA)-29 F.R. 13009, (1964) according to - Category 2
Skin Irritation · Screening - Skin Irrit. 2
Skin Irritation · Authoritative - Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: Appraisal of the safety of chemicals in foods, drugs and cosmetics, FDA (Draize)(1959) according to - High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) individual approach (adopted 22 July 2010) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) dated May 30, 2008 - Classification not possible
Skin Sensitization · Screening - Skin Sens. 1
Skin Sensitization · Authoritative - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Moderate or Mild Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act Regulations, Section 191.12, Federal Register: 29, 13009 (1964). according to - Moderate or Mild Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act Regulations, Section 191.12, Federal Register: 29, 13009 (1964) according to - Category 2B
Eye Irritation · Screening - Eye Irrit. 2
Eye Irritation · Authoritative - Moderate or Mild Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
来源: 美国EPA CompTox
相关文献
- Assessment of the skin sensitising potency of the lower alkyl methacrylate esters. · 2014
- Final Report of the Safety Assessment of Methacrylate Ester Monomers Used in Nail Enhancement Products1 · 2005
- Final report of the safety assessment of methacrylate ester monomers used in nail enhancement products. · 2005