What is this ingredient?

미국 FDA 물질 등록 · UNII V11534UYZ0 · 등록명 ISOBUTYL METHACRYLATE · 단일 화학물질

All ingredients

Ingredient Dictionary

ISOBUTYL METHACRYLATE

How much products actually contain

No product states its amount yet.

Of the products containing it, 0 list it before the 1% line and 1 after it (usually 1% or less).

Products using this ingredient

1 of 1 confirmed · likeliest to carry enough first

R+CoR+Co DAILY FORECAST FINISHING SPRAY

Definition

US FDA substance register · UNII V11534UYZ0 · registered name ISOBUTYL METHACRYLATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Leaves a thin film where appliedFILM FORMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Methacrylate Ester Monomers

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Methacrylate Ester Monomers Used in Nail Enhancement Products

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name メタクリル酸イソブチル: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

ISOBUTYL METHACRYLATEINCI아이소부틸메타크릴레이트Korean label name (MFDS standard)2-Propenoic acid, 2-methyl-, 2-methylpropyl esterSynonymメタクリル酸イソブチルJapanese labelling name

CAS No.chemical registry number: 97-86-9
EC No.EU chemical inventory number: 202-613-0
DTXSIDUS EPA chemical ID: DTXSID3025461
DTXCIDUS EPA compound ID: DTXCID505461

IUPAC: 2-Methylpropyl 2-methylprop-2-enoate
Molecular formula: C8H14O2
Molecular weight: 142.198 g/mol

Measured properties

Appearance: Isobutyl methacrylate is a colorless liquid with a flash point of 120 °F. When heated to high temperatures it may release acrid smoke and fumes. If it is subjected to heat for prolonged periods or becomes contaminated, it is subject to polymerization. If the polymerization takes place inside a container, the container may violently rupture. The vapors are heavier than air. It may be irritating to · CBI, Liquid
Boiling point: 311 °F at 760 mmHg (NTP, 1992) · 155 °C
Melting point: Freezing pt: -61 °C
Solubility: Insoluble (<1mg/ml) (NTP, 1992) · Miscible with ethanol, ethyl ether
Density: 0.8858 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.8858 g/cu cm at 20 °C
Colour: colourless
Melting/freezing point: -61 ℃
Initial boiling point and range: 155 ℃
Flash point: 49 ℃
Vapour pressure: 3.63 ㎜Hg
Water solubility: 439 ㎎/ℓ
Vapour density: 4.91 (at 60℃)
Relative density: 0.8858
n-Octanol/water partition coefficient (Kow): 2.95
Auto-ignition temperature: 390 ℃
Molecular weight: 142.22

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 11 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Monomers3
Intermediate3
Adhesion/cohesion promoter2
Flavouring and nutrient1
Fragrance1
Film former1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

11 skin studies and 7 eye studies are on record.

Classed as moderate2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 18 studies

Category 6.3B (Category 3)
Skin Irritation · Read Across
Severe Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act Regulations, Section 191.12, Federal Register: 29, 13009 (1964). according to
High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Severe Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labelling Act Regulations, Section 191.11, published in the Federal Register (USA)-29 F.R. 13009, (1964) according to
Category 2
Skin Irritation · Screening
Skin Irrit. 2
Skin Irritation · Authoritative
Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: Appraisal of the safety of chemicals in foods, drugs and cosmetics, FDA (Draize)(1959) according to
High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) individual approach (adopted 22 July 2010) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) dated May 30, 2008
Classification not possible
Skin Sensitization · Screening
Skin Sens. 1
Skin Sensitization · Authoritative
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Moderate or Mild Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act Regulations, Section 191.12, Federal Register: 29, 13009 (1964). according to
Moderate or Mild Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act Regulations, Section 191.12, Federal Register: 29, 13009 (1964) according to
Category 2B
Eye Irritation · Screening
Eye Irrit. 2
Eye Irritation · Authoritative
Moderate or Mild Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to