How much products actually contain
No product states its amount yet.
Of the products containing it, 0 list it before the 1% line and 2 after it (usually 1% or less).
Products using this ingredient
2 of 2 confirmed · likeliest to carry enough first
Definition
US FDA substance register · UNII OH3UOW0EHH · registered name ISOBUTYLAMIDO THIAZOLYL RESORCINOL · single chemical substance
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name イソブチラミドチアゾリルレゾルシノール: 本品は、次の化学式で表される複素環式化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 1428450-95-6
- DTXSIDUS EPA chemical ID
- DTXSID901020949
- DTXCIDUS EPA compound ID
- DTXCID301505999
- IUPAC
- N-[4-(2,4-Dihydroxyphenyl)-1,3-thiazol-2-yl]-2-methylpropanamide
- Molecular formula
- C13H14N2O3S
- Molecular weight
- 278.33 g/mol
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Bleaching agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Studies Indicate No Significant Irritation
skin corrosion: in vitro / ex vivo · Screening · OECD Guideline 439 (In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method) adopted in 2013 according to EU Method B.46 (In Vitro Skin Irritation: Reconstructed Human Epidermis Model Test) according to - High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) adopted in 2010 - Studies Indicate No Significant Irritation
eye irritation: in vitro / ex vivo · Screening · OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] equivalent or similar to EU method B.47 (Bovine corneal opacity and permeability test method for identifying ocular corrosives and severe irritants) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
- Allergic Contact Dermatitis to Isobutylamido Thiazolyl Resorcinol (Thiamidol) · 2025
- Clinical Efficacy of the Human Tyrosinase Inhibitor Thiamidol (isobutylamido thiazolyl resorcinol) in Melasma · 2025
- Thiamidol (isobutylamido thiazolyl resorcinol): A Highly Specific Human Tyrosinase Inhibitor for the Treatment of Hyperpigmentation · 2025
- Clinical Evaluation of the Human Tyrosinase Inhibitor Thiamidol (isobutylamido thiazolyl resorcinol) in Prevention of UVB-induced Hyperpigmentation · 2025
- Effective Reduction of Acne-induced Post-inflammatory Hyperpigmentation with the Human Tyrosinase Inhibitor Thiamidol (isobutylamido thiazolyl resorcinol) · 2025
Linked databases 12
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata