Definition
US FDA substance register · UNII 5916QUE93V · registered name ISOLONGIFOLANONE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 23787-90-8
- EC No.EU chemical inventory number
- 245-890-3
- DTXSIDUS EPA chemical ID
- DTXSID2047228
- DTXCIDUS EPA compound ID
- DTXCID0027228
- IUPAC
- 1,1,5,5-Tetramethylhexahydro-2H-2,4a-methanonaphthalen-8(5H)-one
- Molecular formula
- C15H24O
- Molecular weight
- 220.356 g/mol
Measured properties
- Appearance
- liquid
- Melting/freezing point
- &, lt, -20 ℃
- Initial boiling point and range
- 295 ℃(101.9kPa)
- Flash point
- 117 ℃
- Vapour pressure
- 0.87 ㎩ (at 25°C)
- Water solubility
- 0.025 g/㎖ (20°C, pH7)
- Vapour density
- 7.606351397997929
- Relative density
- 1 (20°C)
- n-Octanol/water partition coefficient (Kow)
- 4.7 (log Pow 4.7, 4.9, log Pow 5.1 (25°C)(ECHA))
- Auto-ignition temperature
- 323 ℃ (at &, gt, =99-&, lt, =101hPa)
- Molecular weight
- 220.356
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance6
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Severe Irritation
skin corrosion: in vitro / ex vivo · Screening · OECD Guideline 439 (In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method) according to EU Method B.46 (In Vitro Skin Irritation: Reconstructed Human Epidermis Model Test) according to - Studies Indicate No Significant Irritation
skin corrosion: in vitro / ex vivo · Screening · OECD Guideline 431 (In Vitro Skin Corrosion: Human Skin Model Test) according to other guideline: B.40 Bis of Commission Regulation (EC) No. 440/2008, of 30 May 2008, laying down test methods pursuant to Regulation (EC) No. 1907/2006 of the EuropeanParliament and of the Council on REACH according to - Low to Moderate Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Ambiguous
eye irritation: in vitro / ex vivo · Screening · OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] according to
Source: US EPA CompTox dashboard
Linked databases 10
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata