Gloshell
成分词典

成分词典

ISOOCTYL THIOGLYCOLATE

分子结构

定义

美国FDA 物质登记 · UNII 3404M9ZDTB · 登记名称 ISOOCTYL THIOGLYCOLATE · 单一化学物质

来源: 美国FDA 物质识别码(UNII)

化妆品中的作用

烫卷或拉直头发HAIR WAVING OR STRAIGHTENING

安全与法规参考

限用
中国

来源: 韩国食药处 化妆品法规信息

阿根廷 · 巴西

  • Field of application and/or use : Products for straightening or waving hair: 1. General use 2. Professional use
  • Maximum concentration permitted at final product : 1. 8% ready to use pH 6 to 9,5 2.11% ready to use pH 6 to 9.5 The percentages are calculated as thioglycolic acid
  • Other limitations and requirements : 1) and 2) In the USAGE must consist obligatorily the following information: - May cause sensitization by skin contact. - Avoid contact with eyes. - In case of contact with eyes, rinse immediately and thoroughly with water and consult a doctor. - Wear suitable gloves
  • Use conditions and warnings that must appear on the label : 1) and 2) Contains thioglycolate Follow the instructions Keep out of reach of children. For professional use only (if applicable)

东盟

  • Field of application and/or use : Hair waving or straightening products: 1. General use 2. Professional use
  • Maximum authorised concentration in the finished cosmetic product : 1. 8% ready for use at pH 6-9.5 2. 11% ready for use at pH 6-9.5 Percentages calculated as thioglycolic acid.
  • Other limitations and requirements : The directions for use drawn up in the national or official language(s) must obligatorily incorporate the following sentences: • May cause sensitisation in the event of skin contact. • Avoid contact with eyes. • In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice. • Wear suitable gloves.
  • Conditions of use and warning which must be printed on the labels : • Contains thioglycolate. • Follow the instructions. • Keep out of reach of children. • For professional use only.

欧盟

  • Product Type, body parts : Hair waving or straightening products
  • Maximum concentration in ready for use preparation : (a) 8% (b) 11% The abovementioned percentages are calculated as thioglycollic acid
  • Other : (a) General use ready for use pH 6 to 9.5 (b) Professional use ready for use pH 6 to 9.5
  • Wording of conditions of use and warnings : Conditions of use: (a) (b) May cause sensitization in the event of skin contact Avoid contact with eyes In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice Wear suitable gloves Warnings: Contains thioglycolate Follow the instructions Keep out of reach of children (b) For professional use only

来源: 韩国食药处 化妆品法规信息

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息(环境公团)

加拿大化妆品成分热点清单 · 禁止用于化妆品

来源: 加拿大禁用·限用成分清单

Restriction III/2b · Other restriction: ban substances that deplete the ozone layer

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Final Amended Report on the Safety Assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thioglycolate, Sodium Thioglycolate, and Thioglycolic Acid

来源: 美国CIR 安全性评估

详细资料——标示名称、识别编号、物性、试验记录、文献

别名和识别信息

ISOOCTYL THIOGLYCOLATEINCI아이소옥틸티오글라이콜레이트韩国标示名称(食药处标准名)Acetic acid, mercapto-, isooctyl ester同义名
CAS No.化学物质登记号
25103-09-7
EC No.欧盟化学品目录编号
246-613-9
DTXSID美国EPA化学品编号
DTXSID1027841

实测物性

性状
Liquid · Water-white liquid with a mild fruity odor, [Hawley] Colorless or pale yellow liquid, [HSDB] Clear white liquid, [Aldrich MSDS]
气味
Faint fruity odor
沸点
125 °C @ 17 mm Hg · BP: 80-88 °C (6 kPa)
密度
0.9736 @ 25 °C · Density: 1.04 kg/l @ 20 °C
熔点/凝固点
≤ 31 ℃
初沸点和沸程
124~125 ℃ (at 17mmHg)
闪点
120 ℃((c.c))
蒸气压
0.0138 ㎜Hg (at 25℃ (估算值))
正辛醇/水分配系数(Kow)
3.68 ((估算值))
黏度
3.67 cP (at 20℃)
分子量
204.32

这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。

来源: PubChem · 韩国安全保健公团 安全数据表

产品实际使用的用途

这是向美国 EPA 申报含该成分的 4 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。

  • Chain transfer agent1
  • Hair waving or straightening (EPA)1
  • Chemical reaction regulator1
  • Viscosity modifier1

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 3 项、眼部试验 1 项。

归类为刺激性高1 项归类为中等1 项

各项试验结论不一(最多的结论占 50%),因此不能断定该成分有刺激性。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。

查看全部 4 项试验
  • Moderate or Mild Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • SkinSens1
    Skin Sensitization · QSAR Predicted
  • Moderate or Mild Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to

来源: 美国EPA CompTox

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