Ingredient Dictionary

ISOPROPYL ACETATE

Isopropyl acetate is a carboxylic ester.

How much products actually contain

No product states its amount yet.

Of the products containing it, 2 list it before the 1% line and 1 after it (usually 1% or less).

Products using this ingredient

3 of 3 confirmed · likeliest to carry enough first

Definition

Isopropyl acetate is a carboxylic ester.

Source: PubChem

US FDA substance register · UNII 1Y67AFK870 · registered name Isopropyl Acetate · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Base that dissolves other ingredientsSOLVENT

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Final Report of the Cosmetic Ingredient Reveiw Expert Panel on the Safety Assessment of Methyl Acetate

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name 酢酸イソプロピル: 本品は、酢酸（＊）とイソプロパノール（＊）のエステルであり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

ISOPROPYL ACETATEINCI아이소프로필아세테이트Korean label name (MFDS standard)Acetic acid, 1-methylethyl esterSynonym酢酸イソプロピルJapanese labelling name

CAS No.chemical registry number: 108-21-4
EC No.EU chemical inventory number: 203-561-1
DTXSIDUS EPA chemical ID: DTXSID2025478
DTXCIDUS EPA compound ID: DTXCID605478

IUPAC: Propan-2-yl acetate
Molecular formula: C5H10O2
Molecular weight: 102.133 g/mol

Measured properties

Appearance: Isopropyl acetate appears as a clear colorless liquid. Flash point 40 °F. Vapors are heavier than air. Contact with the material may irritate skin, eyes or mucous membranes. May be toxic by ingestion, inhalation and skin absorption. Used as a solvent. · Liquid, CBI
Odour: Aromatic · ... Fruity odor.
Boiling point: 190 to 196 °F at 743.3 mmHg (NTP, 1992) · 88.6 °C @ 760 MM HG
Melting point: -100.1 °F (NTP, 1992) · -73.4 °C
Solubility: 1 to 10 mg/mL at 68 °F (NTP, 1992) · SOL IN ACETONE, ETHANOL, MISCIBLE IN ETHYL ETHER
Density: 0.874 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.8718 @ 20 °C/4 °C
Colour: colourless
Melting/freezing point: -73 ℃
Initial boiling point and range: 89 ℃
Flash point: 2 ℃
Upper/lower flammability or explosive limits: 7.8 / 1.8 %
Vapour pressure: 60.37 ㎜Hg(25℃)
Water solubility: 4.3 g/100㎖(27℃)
Relative density: 874 (kg/m3)
n-Octanol/water partition coefficient (Kow): 1.28
Auto-ignition temperature: 460 ℃
Viscosity: 0.475 ㎡/s(40℃)
Molecular weight: 102.13

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 19 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Solvent10
Pigment2
Flavouring and nutrient2
Fragrance2
Intermediate1
Plasticizer1
pH regulating agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

6 skin studies and 4 eye studies are on record.

Classed as low3

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 10 studies

Classification not possible
Skin Sensitization · Screening
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) adopted 1981
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Ambiguous
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Not classified
Skin Irritation · Screening
Category 6.3B (Category 3)
Skin Irritation · Read Across
Eye Irrit. 2
Eye Irritation · Authoritative
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Category 2A
Eye Irritation · Screening