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Ingredients

Ingredient Dictionary

ISOPROPYL ALCOHOL

Propan-2-ol is a secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 2,183 list it before the 1% line and 280 after it (usually 1% or less).

Products using this ingredient

12 of 2,459 confirmed · likeliest to carry enough first · See all 2,459

Definition

Propan-2-ol is a secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group. It has a role as a protic solvent. It is a secondary fatty alcohol and a secondary alcohol.

Source: PubChem

US FDA substance register · UNII ND2M416302 · registered name Isopropyl alcohol · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Adjusts thicknessVISCOSITY CONTROLLINGBase that dissolves other ingredientsSOLVENTRemoves unwanted foamANTIFOAMINGGives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Final Report of the Cosmetic Ingredient Reveiw Expert Panel on the Safety Assessment of Methyl Acetate

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name イソプロパノール: 本品は、次の化学式で表される脂肪族アルコールである。

Source: JCIA labelling names (Japan)

Names & identifiers

ISOPROPYL ALCOHOLINCI아이소프로필알코올Korean label name (MFDS standard)2-PropanolSynonymイソプロパノールJapanese labelling name
CAS No.chemical registry number
67-63-0
EC No.EU chemical inventory number
200-661-7
DTXSIDUS EPA chemical ID
DTXSID7020762
DTXCIDUS EPA compound ID
DTXCID50762
IUPAC
Propan-2-ol
Molecular formula
C3H8O
Molecular weight
60.096 g/mol

Measured properties

Appearance
liquid
Colour
colourless
Melting/freezing point
-89.5 ℃
Initial boiling point and range
82.3 ℃
Flash point
23 ℃
Upper/lower flammability or explosive limits
12 / 2 %
Vapour pressure
45.4 ㎜Hg(25℃)
Water solubility
100 g/100㎖
Relative density
0.79
n-Octanol/water partition coefficient (Kow)
0.05
Auto-ignition temperature
456 ℃
Viscosity
2.1 cP(25℃)
Molecular weight
60.0952

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 522 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Solvent228
  • Solubility enhancer157
  • Biocide39
  • Cleaning agent11
  • Surfactant (surface active agent)9
  • Defoamer7
  • Processing aids not otherwise specified7
  • Fragrance6
25 other uses
  • Degradant/impurity (EPA)5
  • Viscosity modifier5
  • Pigment4
  • Corrosion inhibitor4
  • Wetting agent (non-aqueous)4
  • Intermediate4
  • Flavouring and nutrient3
  • Anti-adhesive/cohesive3
  • Soil amendments3
  • Diluent2
  • Demulsifier2
  • Surface modifier2
  • No specific technical function2
  • Fuel2
  • Emulsifier2
  • Lubricating agent2
  • Stabilizing agent1
  • Dispersing agent1
  • Catalyst1
  • Insulators1
  • Flux agent1
  • Chemical reaction regulator1
  • Sealant (barrier)1
  • Drier1
  • Adhesion/cohesion promoter1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 6 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 10 studies
  • Category 6.3B (Category 3)
    Skin Irritation · Read Across
  • Not classified
    Skin Irritation · Screening
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • Classification not possible
    Skin Sensitization · Screening
  • Category 2
    Eye Irritation · Screening
  • Eye Irrit. 2
    Eye Irritation · Authoritative
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across
  • Eye Irrit. 2
    Eye Irritation · Screening
  • Severe Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
  • Serious eye damage/eye irritation - Category 2
    Eye Irritation · Screening

Source: US EPA CompTox dashboard

Related literature

Linked databases 22