Isopropyl tetradecanoate is a fatty acid ester.
How much products actually contain
No product states its amount yet.
Of the products containing it, 352 list it before the 1% line and 107 after it (usually 1% or less).
Products using this ingredient
12 of 443 confirmed · likeliest to carry enough first · See all 443
AROMATICARitual Hair Oil Lavender & Patchouli 50ml
NeutrogenaBody Oil 473ml
Mielle OrganicsMielle Organics Rosemary Mint Scalp & Edge Cleansing Oil
Mielle OrganicsMielle Organics Sea Moss Anti-Shedding Scalp & Hair Oil
VTPDRN Essence 100 30ml
VTPDRN Essence 30ml Special Set, 2 Types
numbuzinNo.1 Clean Sweep Cleansing Oil Jumbo 400ml
medicubePDRN Pink Collagen Glow Jelly Mist Serum 100ml
BioSilk Silk TherapyHeat Enhancer Hair Milk 150ml (2 Types)
medicubePDRN Pink Collagen Jelly Mist 100ml
La Roche-PosayUVIDEA Anthelios Tone Up Rosy Glow 30ml
TIRTIRPorcelain Milk Ampoule
Definition
Isopropyl tetradecanoate is a fatty acid ester.
Source: PubChem
US FDA substance register · UNII 0RE8K4LNJS · registered name ISOPROPYL MYRISTATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments - 2002/2003
Reviewed by CIR: Final Report on the Safety Assessment of Myristyl Myristate and Isopropyl Myristate
Reviewed by CIR: Final Report of the Amended Safety Assessment of Myristic Acid and its Salts and Esters as Used in Cosmetics
Reviewed by CIR: Safety Assessment of Alkyl Esters as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ミリスチン酸イソプロピル: 本品は、ミリスチン酸（＊）とイソプロパノール（＊）のエステルであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 110-27-0
- EC No.EU chemical inventory number
- 203-751-4
- DTXSIDUS EPA chemical ID
- DTXSID0026838
- DTXCIDUS EPA compound ID
- DTXCID306838
- IUPAC
- Propan-2-yl tetradecanoate
- Molecular formula
- C17H34O2
- Molecular weight
- 270.457 g/mol
Measured properties
- Appearance
- Dry Powder, Liquid, CBI, Other Solid · Colorless liquid, [Hawley]
- Odour
- Practically odorless · odourless
- Boiling point
- 588 K (315 °C) at 760 mm Hg · 192.00 to 193.00 °C. @ 20.00 mm Hg
- Melting point
- Approximately 3 °C · 3 °C
- Solubility
- Soluble in castor oil, cottonseed oil, acetone, chloroform, ethyl acetate, ethanol, toluene, and mineral oil, practically insoluble in glycerol, propylene glycol · Soluble in ether, very soluble in acetone, benzene, insoluble in water
- Density
- 0.8532 g/cu cm at 20 °C · 0.847 - 0.855
- Stability
- Withstands oxidn & does not readily become rancid. · ... Trans-esterification and other typical ester reactions may also occur. All of these esters are saturated compounds and would not be expected to autoxidize readily.
- Colour
- colourless
- Melting/freezing point
- 3 ℃
- Initial boiling point and range
- 191~199 ℃ (11 mmHg)
- Flash point
- 165 ℃((o.c.))
- Vapour pressure
- 0 ㎜Hg ((20 ℃))
- Water solubility
- 0.006408 ㎎/ℓ
- Vapour density
- 9.3
- Relative density
- 0.85
- n-Octanol/water partition coefficient (Kow)
- 7.17
- Auto-ignition temperature
- (&, gt, 300 C)
- Viscosity
- 5 cP ((25 ℃))
- Molecular weight
- 270.51
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 296 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance216
- Softener and conditioner33
- Solvent17
- Solubility enhancer9
- Binder5
- Humectant3
- Deodorizer3
- Chemical reaction regulator2
6 other uses
- Diluent2
- Emulsifier2
- Flavouring and nutrient1
- Intermediate1
- Defoamer1
- Lubricating agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) equivalent or similar to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
- Isopropyl Ricinoleate, A Potential Alternative to Isopropyl Myristate: Experimental and Computational evaluation · 2021
- Isopropyl myristate contact allergy: could your moisturizer be the culprit? · 2017
- Isopropyl Myristate and Cocoa Butter are not Appropriate Positive Controls for Comedogenicity Assay in Asian Subjects · 2015
- Synergistic effect of isopropyl myristate and glyceryl monocaprylate on the skin permeation of pentazocine. · 2010
- Effect of amines on the percutaneous absorption of ketoprofen in a lipophilic system consisting of ethanol-isopropyl myristate · 2008
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3 4 5
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese