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Ingredients

Ingredient Dictionary

ISOPROPYLAMINE

Isopropylamine is a member of the class of alkylamines that is propane carrying an amino group at position 2.

Molecular structure

Definition

Isopropylamine is a member of the class of alkylamines that is propane carrying an amino group at position 2. It is a primary aliphatic amine and a member of alkylamines. It is a conjugate base of an isopropylaminium.

Source: PubChem

US FDA substance register · UNII P8W26T4MTD · registered name Isopropylamine · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps pH steadyBUFFERING

Safety & regulatory references

Restricted or banned
China · South Korea

Source: MFDS (Korea) cosmetic regulatory information

Argentina · Brazil

  • Maximum concentration permitted at final product : Under maximum secondary amine: 0.5%
  • Other limitations and requirements : No use with nitrosating systems. Minimum 99% -Pureza. Maximum -Tenor of secondary amines in raw materials 0.5%. Maximum nitrosamine -Tenor: 50 ug / kg. -Envasar / Nitrite - free store in containers.

ASEAN

  • Maximum authorised concentration in the finished cosmetic product : Maximum secondary amine content: 0.5%
  • Other limitations and requirements : • Do not use with nitrosating systems • Minimum purity: 99% • Maximum secondary amine content: 0.5% (applies to raw materials) • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers

European Union

  • Maximum concentration in ready for use preparation : Maximum secondary amine content: 0.5%
  • Other : - Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Restriction III/61

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

ISOPROPYLAMINEINCI아이소프로필아민Korean label name (MFDS standard)2-PropanamineSynonym
CAS No.chemical registry number
75-31-0
EC No.EU chemical inventory number
200-860-9
DTXSIDUS EPA chemical ID
DTXSID2025682
DTXCIDUS EPA compound ID
DTXCID905682
IUPAC
Propan-2-amine
Molecular formula
C3H9N
Molecular weight
59.112 g/mol

Measured properties

Appearance
liquid
Colour
colourless
Odour threshold
0.504 ㎎/㎥
pH
13.1 (50vol%, at 25℃)
Melting/freezing point
&amp, lt, ℃ (1013 hPa)
Initial boiling point and range
32 ℃(1013hPa)
Flash point
≤ ℃
Upper/lower flammability or explosive limits
2.3 / 10 %
Vapour pressure
63100 ㎩ (20℃)
Water solubility
&amp, gt, 50 other: (20℃, % [m/m])
Vapour density
2.04
Relative density
687.1kg/m³ (20℃)
n-Octanol/water partition coefficient (Kow)
0.26
Auto-ignition temperature
355 ℃ (1 016 hPa)
Viscosity
0.47
Molecular weight
59.11

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Flavouring and nutrient2
  • pH regulating agent2
  • Intermediate2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

7 skin studies and 4 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 11 studies
  • Skin corrosion/irritation - Category 1
    Skin Irritation · Screening
  • Skin Irrit. 2
    Skin Irritation · Authoritative
  • Classification not possible
    Skin Sensitization · Screening
  • Category 1A
    Skin Irritation · Screening
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • Category 8.2C (Category 1C)
    Skin Irritation · Read Across
  • Corrosive
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
  • Category 1
    Eye Irritation · Screening
  • Category 8.3A (Category 1)
    Eye Irritation · Read Across
  • Corrosive or Irritation Persists for > 21 days
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
  • Eye Irrit. 2
    Eye Irritation · Authoritative

Source: US EPA CompTox dashboard

Related literature

Linked databases 19