Isopropylamine is a member of the class of alkylamines that is propane carrying an amino group at position 2.
定义
Isopropylamine is a member of the class of alkylamines that is propane carrying an amino group at position 2. It is a primary aliphatic amine and a member of alkylamines. It is a conjugate base of an isopropylaminium.
来源: PubChem
美国FDA 物质登记 · UNII P8W26T4MTD · 登记名称 Isopropylamine · 单一化学物质
化妆品中的作用
安全与法规参考
- 限用·禁用
- 韩国 · 中国
来源: 韩国食药处 化妆品法规信息
阿根廷 · 巴西
- Maximum concentration permitted at final product : Under maximum secondary amine: 0.5%
- Other limitations and requirements : No use with nitrosating systems. Minimum 99% -Pureza. Maximum -Tenor of secondary amines in raw materials 0.5%. Maximum nitrosamine -Tenor: 50 ug / kg. -Envasar / Nitrite - free store in containers.
东盟
- Maximum authorised concentration in the finished cosmetic product : Maximum secondary amine content: 0.5%
- Other limitations and requirements : • Do not use with nitrosating systems • Minimum purity: 99% • Maximum secondary amine content: 0.5% (applies to raw materials) • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers
欧盟
- Maximum concentration in ready for use preparation : Maximum secondary amine content: 0.5%
- Other : - Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers
来源: 韩国食药处 化妆品法规信息
未列入韩国有毒物质 GHS 分类 · 现有化学物质
Restriction III/61
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 75-31-0
- EC No.欧盟化学品目录编号
- 200-860-9
- DTXSID美国EPA化学品编号
- DTXSID2025682
- DTXCID美国EPA化合物编号
- DTXCID905682
- IUPAC
- Propan-2-amine
- 分子式
- C3H9N
- 分子量
- 59.112 g/mol
实测物性
- 性状
- 液体
- 颜色
- 无色
- 嗅觉阈值
- 0.504 ㎎/㎥
- pH
- 13.1 (50vol%, at 25℃)
- 熔点/凝固点
- &, lt, ℃ (1013 hPa)
- 初沸点和沸程
- 32 ℃(1013hPa)
- 闪点
- ≤ ℃
- 燃烧或爆炸范围上限/下限
- 2.3 / 10 %
- 蒸气压
- 63100 ㎩ (20℃)
- 溶解度
- &, gt, 50 other: (20℃, % [m/m])
- 蒸气密度
- 2.04
- 比重
- 687.1kg/m³ (20℃)
- 正辛醇/水分配系数(Kow)
- 0.26
- 自燃温度
- 355 ℃ (1 016 hPa)
- 黏度
- 0.47
- 分子量
- 59.11
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 6 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Flavouring and nutrient2
- pH regulating agent2
- Intermediate2
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 7 项、眼部试验 4 项。
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 11 项试验
- Skin corrosion/irritation - Category 1
Skin Irritation · Screening - Skin Irrit. 2
Skin Irritation · Authoritative - Classification not possible
Skin Sensitization · Screening - Category 1A
Skin Irritation · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Category 1
Eye Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Eye Irrit. 2
Eye Irritation · Authoritative
来源: 美国EPA CompTox
相关文献
- Allergic contact dermatitis caused by herbicide containing glyphosate‐isopropylamine salt · 2022
- Non‐occupational allergic contact dermatitis from epoxy resin in children's games · 2022
- Impact of Glyphosate on the Changes in the mRNA Expression of Neurotransmitters in Experimental Rats · 2022
- Skin Notations for Low-Molecular-Weight Amines: Development of a Testing Protocol with Isopropylamine as an Example · 2018
- Green nanoemulsion-laden glyphosate isopropylamine formulation in suppressing creeping foxglove (A. gangetica), slender button weed (D. ocimifolia) and buffalo grass (P. conjugatum). · 2013