What is this ingredient?

미국 FDA 물질 등록 · UNII 3XK098O8ZW · 등록명 SOLKETAL · 단일 화학물질

All ingredients

Ingredient Dictionary

ISOPROPYLIDENEGLYCEROL

Definition

US FDA substance register · UNII 3XK098O8ZW · registered name SOLKETAL · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Isopropylideneglycerol is the heterocyclic compound that conforms to the formula

Cosmetic roles

Softens hairHAIR CONDITIONING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name イソプロピリデングリセロール: 本品は、次の化学式で表される複素環式化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

ISOPROPYLIDENEGLYCEROLINCI아이소프로필리덴글리세롤Korean label name (MFDS standard)1,3-Dioxolane-4-methanol, 2,2-dimethyl-SynonymイソプロピリデングリセロールJapanese labelling name

CAS No.chemical registry number: 100-79-8
EC No.EU chemical inventory number: 202-888-7
DTXSIDUS EPA chemical ID: DTXSID9021845
DTXCIDUS EPA compound ID: DTXCID901845

IUPAC: (2,2-Dimethyl-1,3-dioxolan-4-yl)methanol
Molecular formula: C6H12O3
Molecular weight: 132.159 g/mol

Measured properties

Appearance: liquid
Colour: colourless
Odour: odourless
Melting/freezing point: &amp, lt, -50 ℃ ( OECD Guideline 102 (Melting point / Melting Range), GLP)
Initial boiling point and range: 192.3 ℃( at 101 325 Pa)
Flash point: 90 ℃
Flammability (solid, gas): combustible
Vapour pressure: 107 ㎜Hg(@ 25 ℃)
Water solubility: 35500 ㎎/ℓ(@ 25 ℃, est.)
Vapour density: 4.6
Relative density: 1.06
n-Octanol/water partition coefficient (Kow): -0.6 (@ 20 ℃)
Auto-ignition temperature: 390 ℃(@ 1005.3~1007.4 hPa)
Viscosity: 11.9 cP(@ 20 ℃, calc.)
Molecular weight: 132.16

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 95 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance74
Solvent21

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 2 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 4 studies

Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to