Gloshell
Ingredients
All ingredients

Ingredient Dictionary

ISOPROPYLPARABEN

Isopropylparaben is a 4-hydroxybenzoate ester.

Molecular structure

Definition

Isopropylparaben is a 4-hydroxybenzoate ester.

Source: PubChem

US FDA substance register · UNII A6EOX47QK0 · registered name ISOPROPYLPARABEN · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Stops microbes growing in the productPRESERVATIVE

Safety & regulatory references

Banned
ASEAN · China · European Union · United Kingdom
Restricted or banned
Argentina · ASEAN · Brazil · China · European Union · Japan · South Korea

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)

EU Cosmetics Regulation, Annex II (prohibited substances), entry 1374

Source: EU prohibited substances (Annex II)

Restriction II/1374 Commission Regulation (EU) No 358/2014 of 9 April 2014

Source: EU CosIng ingredient list

Reviewed by CIR: Final Amended Report on the Safety Assessment of Methylparaben, Ethylparaben, Propylparaben, Isopropylparaben, Butylparaben, Isobutylparaben and Benzylparaben as used in cosmetic products

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Amended Safety Assessment of Parabens as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Isobutylparaben and Isopropylparaben

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name イソプロピルパラベン: 本品は、パラヒドロキシ安息香酸のイソプロピルエステルであり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

ISOPROPYLPARABENINCI아이소프로필파라벤Korean label name (MFDS standard)Benzoic acid, 4-hydroxy-, 1-methylethyl esterSynonymイソプロピルパラベンJapanese labelling name
CAS No.chemical registry number
4191-73-5
EC No.EU chemical inventory number
224-069-3
DTXSIDUS EPA chemical ID
DTXSID3052858
DTXCIDUS EPA compound ID
DTXCID0031269
IUPAC
Propan-2-yl 4-hydroxybenzoate
Molecular formula
C10H12O3
Molecular weight
180.203 g/mol

Measured properties

Appearance
solid
Odour
odourless
Melting/freezing point
97~99 ℃
Initial boiling point and range
275.59 ℃
Flash point
176.063 ℃
Vapour pressure
0.155 ㎩ (25℃)
Water solubility
689.7 ㎎/ℓ (25℃)
Vapour density
6.220227821884708
Relative density
1.132
n-Octanol/water partition coefficient (Kow)
2.91
Molecular weight
180.2

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Preservative2
  • Processing aids not otherwise specified1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · other guideline: CTFA Guidelines according to
  • SkinSens1
    Skin Sensitization · QSAR Predicted
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · other guideline: as mentioned below according to

Source: US EPA CompTox dashboard

Related literature

Linked databases 25

Community

Post a question: Gloshell AI answers first, then other members join in.