Kaempferol is a tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4'.
How much products actually contain
No product states its amount yet.
Of the products containing it, 4 list it before the 1% line and 4 after it (usually 1% or less).
Products using this ingredient
8 of 8 confirmed · likeliest to carry enough first
NaturiumNaturium Quadruple Hyaluronic Acid Serum 5%
NaturiumNaturium Quadruple Hyaluronic Acid Serum 5% - Jumbo
SidmoolCalendula Ampoule Moisture Cream
CIRACLEVitamin Source C25 O Serum
CIRACLEVitamin Source C30 O Serum
LEEYUNLeeYun Repair Lotion
NutselineAroma Nut Slim Fit Oil Wash 315ml
NutselineAroma Nut Slim Fit Gua Sha Serum 60ml Single/Set
Definition
Kaempferol is a tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4'. Acting as an antioxidant by reducing oxidative stress, it is currently under consideration as a possible cancer treatment. It has a role as a geroprotector, an antibacterial agent, a plant metabolite, a human xenobiotic metabolite, a human urinary metabolite and a human blood serum metabolite. It is a member of flavonols, a tetrahydroxyflavone and a 7-hydroxyflavonol. It is a conjugate acid of a kaempferol oxoanion.
Source: PubChem
US FDA substance register · UNII 731P2LE49E · registered name KAEMPFEROL · single chemical substance
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ケンフェロール: 本品は、次の化学式で表される複素環式化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 520-18-3
- EC No.EU chemical inventory number
- 208-287-6
- DTXSIDUS EPA chemical ID
- DTXSID7020768
- DTXCIDUS EPA compound ID
- DTXCID30768
- IUPAC
- 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
- Molecular formula
- C15H10O6
- Molecular weight
- 286.239 g/mol
Measured properties
- Appearance
- Solid · Yellow needles from alcohol and water
- Melting point
- 277 °C · MP: 276-278 °C and 278-280 °C decomposes
- Solubility
- Soluble in hot alcohol, ether or alkalies · Insoluble in benzene, slightly soluble in chloroform, soluble in acetic acid, alkalies, very soluble in ethanol, ethyl ether, acetone
- Colour
- Yellow powder
- Melting/freezing point
- 277 ℃
- n-Octanol/water partition coefficient (Kow)
- 1.960
- Molecular weight
- 286.25
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
- Antioxidant1
Source: US EPA CompTox dashboard
Related literature
- Evaluation of Safety and Antigenotoxic Activity of Rosa centifolia Extract, Kaempferol, and Kaempferol-3-glucoside against Ultraviolet B Radiation in Human Fibroblasts · 2025
- Kaempferol: Topical Applications and Nanoformulations in the Treatment of Diseases · 2023
- Inhibitory effect of kaempferol on mouse melanoma cell line B16 in vivo and in vitro · 2020
- Kaempferol: A Key Emphasis to Its Anticancer Potential · 2019
- Inhibitory effect of kaempferol on skin fibrosis in systemic sclerosis by the suppression of oxidative stress. · 2019
Linked databases 18
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- IARC carcinogen classification
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese