Ingredient Dictionary

KETOGLUTARIC ACID

2-oxoglutaric acid is an oxo dicarboxylic acid that consists of glutaric acid bearing an oxo substituent at position 2.

How much products actually contain

No product states its amount yet.

Of the products containing it, 1 list it before the 1% line and 0 after it (usually 1% or less).

Products using this ingredient

1 of 1 confirmed · likeliest to carry enough first

Ursa MajorUrsa Major Alpine Rich Cream

Definition

2-oxoglutaric acid is an oxo dicarboxylic acid that consists of glutaric acid bearing an oxo substituent at position 2. It is an intermediate metabolite in Krebs cycle. It has a role as a fundamental metabolite. It is functionally related to a glutaric acid. It is a conjugate acid of a 2-oxoglutarate(1-).

Source: PubChem

US FDA substance register · UNII 8ID597Z82X · registered name OXOGLURIC ACID · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Reduces body odourDEODORANT

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ケトグルタル酸: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

KETOGLUTARIC ACIDINCI케토글루타릭애씨드Korean label name (MFDS standard)Pentanedioic acid, 2-oxo-Synonymケトグルタル酸Japanese labelling name

CAS No.chemical registry number: 328-50-7
EC No.EU chemical inventory number: 206-330-3
DTXSIDUS EPA chemical ID: DTXSID5033179
DTXCIDUS EPA compound ID: DTXCID3013179

IUPAC: 2-Oxopentanedioic acid
Molecular formula: C5H6O5
Molecular weight: 146.098 g/mol

Measured properties

Appearance: Solid, [Merck Index] White to off-white solid, [Acros Organics MSDS] · Solid
Boiling point: 323 °C
Melting point: 114 °C (237 °F) · 115.5 °C
Solubility: 100 g/l at 20 °C (68 °F) · 541.5 mg/mL
Colour: white
Melting/freezing point: 115.5 ℃
Vapour density: 5.0
n-Octanol/water partition coefficient (Kow): -2.08 (est.)
Molecular weight: 146.1

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Flavouring and nutrient2
Deodorizer1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 2 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) adopted 1981 according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) equivalent or similar to
Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) adopted 1981 according to
Category 8.3A (Category 1)
Eye Irritation · Read Across