(-)-menthone is a menthone that is cyclohexanone substituted by a methyl and an isopropyl group at positions 5 and 2 respectively (the 2S,5R-stereoisomer).
Definition
US FDA substance register · UNII 5F709W4OG4 · registered name MENTHONE, (-)- · single chemical substance
(-)-menthone is a menthone that is cyclohexanone substituted by a methyl and an isopropyl group at positions 5 and 2 respectively (the 2S,5R-stereoisomer). It is an enantiomer of a (+)-menthone.
Source: PubChem
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 14073-97-3
- EC No.EU chemical inventory number
- 237-926-1
- DTXSIDUS EPA chemical ID
- DTXSID3044384
- DTXCIDUS EPA compound ID
- DTXCID1024384
- IUPAC
- (2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexan-1-one
- Molecular formula
- C10H18O
- Molecular weight
- 154.253 g/mol
Measured properties
- Appearance
- Liquid · Colorless liquid with a mild odor of peppermint, [Hawley]
- Odour
- Slight peppermint odor · CHARACTERISTIC ODOR SIMILAR TO MENTHOL
- Boiling point
- 210 °C · 207.00 to 210.00 °C. @ 760.00 mm Hg
- Melting point
- -6 °C
- Solubility
- Slightly sol in water, sol in org solvents /L-form/ · SOL IN ALC, ETHER, ACETONE, ACETIC ACID, ALL PROP IN BENZENE, SLIGHTLY SOL IN WATER /D & DL-FORMS/
- Density
- 0.888-0.895
- Melting/freezing point
- &, lt, ℃
- Initial boiling point and range
- 210.7 ℃
- Flash point
- 74 ℃
- Vapour pressure
- 80 ㎩ (25°C)
- Water solubility
- 531 ㎎/ℓ
- Vapour density
- 5.3244735933724545
- n-Octanol/water partition coefficient (Kow)
- -1.478
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 9 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance9
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
Source: US EPA CompTox dashboard