Lanosterol is a tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position.
Definition
Lanosterol is a tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, a plant metabolite, a bacterial metabolite and a human metabolite. It is a 14alpha-methyl steroid, a tetracyclic triterpenoid and a 3beta-sterol. It derives from a hydride of a lanostane.
Source: PubChem
US FDA substance register · UNII 1J05Z83K3M · registered name LANOSTEROL · single chemical substance
Lanosta-8,24-dien-3-ol, (3.beta.)-
Cosmetic roles
Safety & regulatory references
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ラノステロール: 本品は、ラノリン（＊）から得られるステロールであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 79-63-0
- EC No.EU chemical inventory number
- 201-214-9
- DTXSIDUS EPA chemical ID
- DTXSID1040744
- DTXCIDUS EPA compound ID
- DTXCID9020744
- IUPAC
- Lanosta-8,24-dien-3beta-ol
- Molecular formula
- C30H50O
- Molecular weight
- 426.729 g/mol
Measured properties
- Appearance
- Solid
- Melting point
- 140.5 °C
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner3
- Anti-static agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- SkinIrr2
Skin Irritation · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
- Impaired cortical actin dynamics via lanosterol-dependent HMG-CoA reductase downregulation mediates IFN-α-induced mast cell stabilization · 2026
- Ocular delivery of lipid nanoparticles-formulated mRNA encoding lanosterol synthase ameliorates cataract in rats · 2025
- Using genetics to investigate the association between lanosterol and cataract · 2024
- Cassia alata L.: A Study of Antifungal Activity against Malassezia furfur, Identification of Major Compounds, and Molecular Docking to Lanosterol 14-Alpha Demethylase · 2024
- Laboratory evaluation of Clusia fluminensis extracts and their isolated compounds against Dysdercus peruvianus and Oncopeltus fasciatus · 2017
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese