Benzododecinium chloride is the organic chloride salt of benzododecinium.
Definition
Benzododecinium chloride is the organic chloride salt of benzododecinium. It has antiseptic and disinfectant properties, and used as a preservative in eye drop formulations. It has a role as a surfactant, an antiseptic drug, a disinfectant and an antifouling biocide. It is a quaternary ammonium salt and an organic chloride salt. It contains a benzododecinium.
Source: PubChem
US FDA substance register · UNII Y5A751G47H · registered name BENZODODECINIUM CHLORIDE · single chemical substance
Cosmetic roles
Safety & regulatory references
- Restricted
- China · South Korea
Source: MFDS (Korea) cosmetic regulatory information
Argentina · Brazil
- Field of application and/or use : (a) care products rinse the hair with (b) Other products
- Maximum concentration permitted at final product : a) 3% (calculated as benzalkonium chloride) b) 0.1% (calculated as benzalkonium chloride)
- Other limitations and requirements : a.- In the finished product, the concentrations of chloride, bromide and saccharinate aliphatic chain with carbon atom number of 14 or less, should not exceed 0.1% (calculated as benzalkonium chloride).
- Use conditions and warnings that must appear on the label : to. and b. - Avoid contact with eyes
- Maximum concentration permitted at final product : 0.1% calculated as benzalkonium chloride
- Use conditions and warnings that must appear on the label : Avoid contact with eyes
European Union
- Product Type, body parts : Rinse-off hair (head) products
- Maximum concentration in ready for use preparation : 3% (as benzalkonium chloride)
- Other : In the final products the concentrations of benzalkonium chloride, bromide and saccharinate with an alkyl chain of C14, or less must not exceed 0.1% (as benzalkonium chloride) For purposes other than inhibiting the development of micro-organismes in the product. This purpose has to be apparent from the presentation of the product
- Wording of conditions of use and warnings : Avoid contact with the eyes
- Maximum concentration in ready for use preparation : 0.1% (as benzalkonium chloride)
- Wording of conditions of use and warnings : Avoid contact with eyes
Source: MFDS (Korea) cosmetic regulatory information
Korea’s toxic-substance GHS classification: Danger · H330 (category 2) · H301 (category 3) · H400 (category 1)
Restriction V/54
Source: EU CosIng ingredient list
Reviewed by CIR: Tentative Report: Safety Assessment of Alkonium Chlorides and Bromides as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 139-07-1
- EC No.EU chemical inventory number
- 205-351-5
- DTXSIDUS EPA chemical ID
- DTXSID2040787
- DTXCIDUS EPA compound ID
- DTXCID7014317
- IUPAC
- N-Benzyl-N,N-dimethyldodecan-1-aminium chloride
- Molecular formula
- C21H38ClN
- Molecular weight
- 339.99 g/mol
Measured properties
- Appearance
- solid
- Melting/freezing point
- 40~50 ℃
- Vapour pressure
- 0.0075 ㎜Hg (@ 100 °C)
- Water solubility
- 22.5 ㎎/ℓ
- n-Octanol/water partition coefficient (Kow)
- 2.93
- Molecular weight
- 181.32
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Biocide1
- Anti-static agent1
- Preservative1
- Surfactant (surface active agent)1
- Processing aids not otherwise specified1
- Corrosion inhibitor1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- PubChem
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata