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成分词典

成分词典

LAURALKONIUM CHLORIDE

Benzododecinium chloride is the organic chloride salt of benzododecinium.

分子结构

定义

Benzododecinium chloride is the organic chloride salt of benzododecinium. It has antiseptic and disinfectant properties, and used as a preservative in eye drop formulations. It has a role as a surfactant, an antiseptic drug, a disinfectant and an antifouling biocide. It is a quaternary ammonium salt and an organic chloride salt. It contains a benzododecinium.

来源: PubChem

美国FDA 物质登记 · UNII Y5A751G47H · 登记名称 BENZODODECINIUM CHLORIDE · 单一化学物质

来源: 美国FDA 物质识别码(UNII)

化妆品中的作用

减少静电ANTISTATIC防止产品中微生物滋生PRESERVATIVE

安全与法规参考

限用
韩国 · 中国

来源: 韩国食药处 化妆品法规信息

阿根廷 · 巴西

  • Field of application and/or use : (a) care products rinse the hair with (b) Other products
  • Maximum concentration permitted at final product : a) 3% (calculated as benzalkonium chloride) b) 0.1% (calculated as benzalkonium chloride)
  • Other limitations and requirements : a.- In the finished product, the concentrations of chloride, bromide and saccharinate aliphatic chain with carbon atom number of 14 or less, should not exceed 0.1% (calculated as benzalkonium chloride).
  • Use conditions and warnings that must appear on the label : to. and b. - Avoid contact with eyes
  • Maximum concentration permitted at final product : 0.1% calculated as benzalkonium chloride
  • Use conditions and warnings that must appear on the label : Avoid contact with eyes

欧盟

  • Product Type, body parts : Rinse-off hair (head) products
  • Maximum concentration in ready for use preparation : 3% (as benzalkonium chloride)
  • Other : In the final products the concentrations of benzalkonium chloride, bromide and saccharinate with an alkyl chain of C14, or less must not exceed 0.1% (as benzalkonium chloride) For purposes other than inhibiting the development of micro-organismes in the product. This purpose has to be apparent from the presentation of the product
  • Wording of conditions of use and warnings : Avoid contact with the eyes
  • Maximum concentration in ready for use preparation : 0.1% (as benzalkonium chloride)
  • Wording of conditions of use and warnings : Avoid contact with eyes

来源: 韩国食药处 化妆品法规信息

韩国有毒物质 GHS 分类: 危险 · H330 (第2类) · H301 (第3类) · H400 (第1类)

来源: 韩国有毒物质 GHS 信息(环境公团)

Restriction V/54

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Tentative Report: Safety Assessment of Alkonium Chlorides and Bromides as Used in Cosmetics

来源: 美国CIR 安全性评估

详细资料——标示名称、识别编号、物性、试验记录、文献

别名和识别信息

LAURALKONIUM CHLORIDEINCI라우랄코늄클로라이드韩国标示名称(食药处标准名)Benzenemethanaminium, N-dodecyl-N,N-dimethyl-, chloride同义名
CAS No.化学物质登记号
139-07-1
EC No.欧盟化学品目录编号
205-351-5
DTXSID美国EPA化学品编号
DTXSID2040787
DTXCID美国EPA化合物编号
DTXCID7014317
IUPAC
N-Benzyl-N,N-dimethyldodecan-1-aminium chloride
分子式
C21H38ClN
分子量
339.99 g/mol

实测物性

性状
固体
熔点/凝固点
40~50 ℃
蒸气压
0.0075 ㎜Hg (@ 100 °C)
溶解度
22.5 ㎎/ℓ
正辛醇/水分配系数(Kow)
2.93
分子量
181.32

这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。

来源: 韩国安全保健公团 安全数据表

产品实际使用的用途

这是向美国 EPA 申报含该成分的 6 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。

  • Biocide1
  • Anti-static agent1
  • Preservative1
  • Surfactant (surface active agent)1
  • Processing aids not otherwise specified1
  • Corrosion inhibitor1

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 1 项、眼部试验 1 项。

归类为中等1 项

试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。

查看全部 2 项试验
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across

来源: 美国EPA CompTox

关联数据库 18