Benzododecinium chloride is the organic chloride salt of benzododecinium.
定义
Benzododecinium chloride is the organic chloride salt of benzododecinium. It has antiseptic and disinfectant properties, and used as a preservative in eye drop formulations. It has a role as a surfactant, an antiseptic drug, a disinfectant and an antifouling biocide. It is a quaternary ammonium salt and an organic chloride salt. It contains a benzododecinium.
来源: PubChem
美国FDA 物质登记 · UNII Y5A751G47H · 登记名称 BENZODODECINIUM CHLORIDE · 单一化学物质
化妆品中的作用
安全与法规参考
- 限用
- 韩国 · 中国
来源: 韩国食药处 化妆品法规信息
阿根廷 · 巴西
- Field of application and/or use : (a) care products rinse the hair with (b) Other products
- Maximum concentration permitted at final product : a) 3% (calculated as benzalkonium chloride) b) 0.1% (calculated as benzalkonium chloride)
- Other limitations and requirements : a.- In the finished product, the concentrations of chloride, bromide and saccharinate aliphatic chain with carbon atom number of 14 or less, should not exceed 0.1% (calculated as benzalkonium chloride).
- Use conditions and warnings that must appear on the label : to. and b. - Avoid contact with eyes
- Maximum concentration permitted at final product : 0.1% calculated as benzalkonium chloride
- Use conditions and warnings that must appear on the label : Avoid contact with eyes
欧盟
- Product Type, body parts : Rinse-off hair (head) products
- Maximum concentration in ready for use preparation : 3% (as benzalkonium chloride)
- Other : In the final products the concentrations of benzalkonium chloride, bromide and saccharinate with an alkyl chain of C14, or less must not exceed 0.1% (as benzalkonium chloride) For purposes other than inhibiting the development of micro-organismes in the product. This purpose has to be apparent from the presentation of the product
- Wording of conditions of use and warnings : Avoid contact with the eyes
- Maximum concentration in ready for use preparation : 0.1% (as benzalkonium chloride)
- Wording of conditions of use and warnings : Avoid contact with eyes
来源: 韩国食药处 化妆品法规信息
韩国有毒物质 GHS 分类: 危险 · H330 (第2类) · H301 (第3类) · H400 (第1类)
Restriction V/54
来源: 欧盟 CosIng 成分清单
Reviewed by CIR: Tentative Report: Safety Assessment of Alkonium Chlorides and Bromides as Used in Cosmetics
来源: 美国CIR 安全性评估
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 139-07-1
- EC No.欧盟化学品目录编号
- 205-351-5
- DTXSID美国EPA化学品编号
- DTXSID2040787
- DTXCID美国EPA化合物编号
- DTXCID7014317
- IUPAC
- N-Benzyl-N,N-dimethyldodecan-1-aminium chloride
- 分子式
- C21H38ClN
- 分子量
- 339.99 g/mol
实测物性
- 性状
- 固体
- 熔点/凝固点
- 40~50 ℃
- 蒸气压
- 0.0075 ㎜Hg (@ 100 °C)
- 溶解度
- 22.5 ㎎/ℓ
- 正辛醇/水分配系数(Kow)
- 2.93
- 分子量
- 181.32
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 6 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Biocide1
- Anti-static agent1
- Preservative1
- Surfactant (surface active agent)1
- Processing aids not otherwise specified1
- Corrosion inhibitor1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 1 项、眼部试验 1 项。
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 2 项试验
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
来源: 美国EPA CompTox