Ingredient Dictionary

LAURAMINE OXIDE

Dodecyldimethylamine N-oxide is a tertiary amine oxide resulting from the formal oxidation of the amino group of dodecyldimethylamine.

How much products actually contain

No product states its amount yet.

Of the products containing it, 2 list it before the 1% line and 0 after it (usually 1% or less).

Products using this ingredient

2 of 2 confirmed · likeliest to carry enough first

Definition

Dodecyldimethylamine N-oxide is a tertiary amine oxide resulting from the formal oxidation of the amino group of dodecyldimethylamine. It has a role as a detergent and a plant metabolite. It derives from a hydride of a dodecane.

Source: PubChem

US FDA substance register · UNII 4F6FC4MI8W · registered name LAURAMINE OXIDE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Boosts latherSURFACTANT - FOAM BOOSTINGHelps poorly soluble ingredients dissolve in waterSURFACTANT - HYDROTROPESurfactant that lifts dirtSURFACTANT - CLEANSINGSoftens hairHAIR CONDITIONINGGives the product a scentPERFUMINGWashes away surface impuritiesCLEANSINGAdjusts thicknessVISCOSITY CONTROLLINGReduces staticANTISTATIC

Safety & regulatory references

Korea’s toxic-substance GHS classification: Danger · H410 (category 1) · H302 (category 4) · H314 (category 1B) · +1 more

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2007-2010

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Lauramine Oxide and Stearamine Oxide

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ラウラミンオキシド: 本品は、次の化学式で表される第三アミンのオキシドである。

Source: JCIA labelling names (Japan)

Names & identifiers

LAURAMINE OXIDEINCI라우라민옥사이드Korean label name (MFDS standard)1-Dodecanamine, N,N-dimethyl-, N-oxideSynonymラウラミンオキシドJapanese labelling name

CAS No.chemical registry number: 1643-20-5
CAS No.chemical registry number: 308062-28-4
EC No.EU chemical inventory number: 216-700-6
DTXSIDUS EPA chemical ID: DTXSID1020514
DTXCIDUS EPA compound ID: DTXCID8042

IUPAC: N,N-Dimethyldodecan-1-amine N-oxide
Molecular formula: C14H31NO
Molecular weight: 229.408 g/mol

Measured properties

Appearance: Dimethyldodecylamine-n-oxide is a crystalline solid. · Liquid, CBI
Melting point: 266 to 268 °F (NTP, 1992) · 130.5 °C
Solubility: In water, 190,000 mg/L at 25 °C
Stability: Stable at high concentrations of electrolytes and over a wide pH range /Monohydrate/
Melting/freezing point: 132~133 ℃
Vapour pressure: 6.23E-08 ㎜Hg (25℃ (est.))
Water solubility: 19 g/100㎖ (25℃)
n-Octanol/water partition coefficient (Kow): 4.67 (est.)
Molecular weight: 229.41

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 554 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Surfactant (surface active agent)202
Cleaning agent100
Emulsifier76
Foamant54
Thickening agent51
Stabilizing agent51
Wetting agent (non-aqueous)5
Fragrance4

6 other uses

Softener and conditioner3
Anti-static agent2
Solubility enhancer2
Viscosity modifier2
Intermediate1
Biocide1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 2 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 6 studies

Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Classification not possible
Skin Irritation · Screening
Category 8.2B (Category 1B)
Skin Irritation · Read Across
Not classified
Skin Sensitization · Screening
Category 8.3A (Category 1)
Eye Irritation · Read Across
Category 2A
Eye Irritation · Screening