Dodecylamine is a primary aliphatic amine.
定义
Dodecylamine is a primary aliphatic amine.
来源: PubChem
美国FDA 物质登记 · UNII YWY9OD6A2K · 登记名称 DODECYLAMINE · 单一化学物质
化妆品中的作用
安全与法规参考
- 限用·禁用
- 韩国 · 中国
来源: 韩国食药处 化妆品法规信息
阿根廷 · 巴西
- Maximum concentration permitted at final product : Under maximum secondary amine: 0.5%
- Other limitations and requirements : No use with nitrosating systems. Minimum 99% -Pureza. Maximum -Tenor of secondary amines in raw materials 0.5%. Maximum nitrosamine -Tenor: 50 ug / kg. -Envasar / Nitrite - free store in containers.
东盟
- Maximum authorised concentration in the finished cosmetic product : Maximum secondary amine content: 0.5%
- Other limitations and requirements : • Do not use with nitrosating systems • Minimum purity: 99% • Maximum secondary amine content: 0.5% (applies to raw materials) • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers
欧盟
- Maximum concentration in ready for use preparation : Maximum secondary amine content: 0.5%
- Other : - Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers
来源: 韩国食药处 化妆品法规信息
未列入韩国有毒物质 GHS 分类 · 现有化学物质
Restriction III/61
来源: 欧盟 CosIng 成分清单
Reviewed by CIR: Final Report on the Safety Assessment of Lauramine and Stearamine
来源: 美国CIR 安全性评估
CIR reviewed this ingredient and flagged its status as: Insufficient data ingredients with no uses reported to FDA's Voluntary Cosmetic Registration Program (VCRP) (insufficient data or use not supported — CIR's own classification, not a full safety-as-used conclusion).
来源: 美国CIR 安全性评估
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 124-22-1
- EC No.欧盟化学品目录编号
- 204-690-6
- DTXSID美国EPA化学品编号
- DTXSID3021984
- DTXCID美国EPA化合物编号
- DTXCID901984
- IUPAC
- Dodecan-1-amine
- 分子式
- C12H27N
- 分子量
- 185.355 g/mol
实测物性
- 性状
- Dodecanamine appears as a yellow liquid with an ammonia-like odor. Insoluble in water and less dense than water. Hence floats on water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion, inhalation or skin absorption. Used to make other chemicals. · Other Solid, Liquid
- 气味
- AMINE ODOR
- 沸点
- 259 °C
- 熔点
- 28.3 °C · 28 °C
- 溶解性
- Miscible in ethanol, ethyl ether, and benzene. · In water, 0.078 g/l at 25 °C and pH 11.8.
- 密度
- 0.8015 g/cu cm @ 20 °C/4 °C · 0.81 g/cm³
- 熔点/凝固点
- 28.3 ℃
- 初沸点和沸程
- 259 ℃
- 闪点
- &, gt, 110 ℃
- 燃烧或爆炸范围上限/下限
- 5.1 / 0.6 %
- 蒸气压
- 0.000805 ㎜Hg ( at 25 C)
- 溶解度
- 78 ㎎/ℓ ( at 25C)
- 比重
- 0.81
- 正辛醇/水分配系数(Kow)
- 4.76 ((估算值))
- 分子量
- 185.35
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 6 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Corrosion inhibitor2
- Intermediate2
- pH regulating agent1
- Anti-static agent1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 4 项、眼部试验 0 项。
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 4 项试验
- Category 8.2C (Category 1C)
Skin Irritation · Read Across - Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - SkinSens1
Skin Sensitization · QSAR Predicted - SkinIrr2
Skin Irritation · QSAR Predicted
来源: 美国EPA CompTox
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- Final Report on the Safety Assessment of Dimethyl Lauramine · 1995