1,2-dodecanediol is a medium-chain primary fatty alcohol that is dodecane carrying hydroxy groups at positions 1 and 2.
Definition
1,2-dodecanediol is a medium-chain primary fatty alcohol that is dodecane carrying hydroxy groups at positions 1 and 2. It has a role as an antibacterial agent and an antifungal agent. It is a medium-chain primary fatty alcohol, a secondary fatty alcohol and a dodecanediol.
Source: PubChem
US FDA substance register · UNII EMM0U4H102 · registered name LAURYL GLYCOL · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Reviewed by CIR: Safety Assessment of 1,2-Glycols as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ラウリルグリコール: 本品は、次の化学式で表されるジオールである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 1119-87-5
- EC No.EU chemical inventory number
- 214-289-8
- DTXSIDUS EPA chemical ID
- DTXSID30862552
- DTXCIDUS EPA compound ID
- DTXCID20811296
- IUPAC
- Dodecane-1,2-diol
- Molecular formula
- C12H26O2
- Molecular weight
- 202.338 g/mol
Measured properties
- Appearance
- solid
- Colour
- white
- Melting/freezing point
- 58~60 ℃
- Flash point
- &, gt, 140 ℃
- Water solubility
- &, lt, 0.01 g/ℓ (20℃)
- n-Octanol/water partition coefficient (Kow)
- 3.803
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner3
- Anti-static agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- SkinIrr2
Skin Irritation · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata