1-dodecylpyrrolidin-2-one is pyrrolidin-2-one substituted at nitrogen by an n-dodecyl group.
How much products actually contain
No product states its amount yet.
Of the products containing it, 0 list it before the 1% line and 1 after it (usually 1% or less).
Products using this ingredient
1 of 1 confirmed · likeliest to carry enough first
Definition
1-dodecylpyrrolidin-2-one is pyrrolidin-2-one substituted at nitrogen by an n-dodecyl group. It has a role as an epitope.
Source: PubChem
US FDA substance register · UNII 3P14VW8FNY · registered name LAURYL PYRROLIDONE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ラウリルピロリドン: 本品は、次の化学式で表される複素環式化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 2687-96-9
- EC No.EU chemical inventory number
- 403-730-1
- DTXSIDUS EPA chemical ID
- DTXSID4042206
- DTXCIDUS EPA compound ID
- DTXCID2022206
- IUPAC
- 1-Dodecylpyrrolidin-2-one
- Molecular formula
- C16H31NO
- Molecular weight
- 253.43 g/mol
Measured properties
- Appearance
- Liquid · liquid
- Odour
- odourless
- Melting/freezing point
- 124.24 ℃
- Initial boiling point and range
- 202 ℃
- Flash point
- &, gt, 110 ℃
- Vapour pressure
- 0.0000519 ㎜Hg
- Water solubility
- 5.42 ㎎/ℓ
- Relative density
- 0.89
- n-Octanol/water partition coefficient (Kow)
- 4.20 (est.)
- Molecular weight
- 253.43
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 18 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Surfactant (surface active agent)6
- Softener and conditioner3
- Cleaning agent2
- Solvent2
- Soil amendments1
- Dispersing agent1
- Wetting agent (non-aqueous)1
- Processing aids not otherwise specified1
1 other uses
- Plasticizer1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
8 skin studies and 2 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 10 studies
- Skin Corr. 1B
Skin Irritation · Authoritative - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Corrosive
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Act, CFR 16, Section 1500.41 equivalent or similar to - Corrosive
skin irritation: in vivo · Screening · other guideline: Based upon method of Draize et. al. (Draize is famous for designing this study type upon which current in-vivo OECD guidelines are based) according to - Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: Modification of procedure of Draize et. al. according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Category 6.5B (Category 1)
Skin Sensitization · Read Across - Skin Sens. 1
Skin Sensitization · Authoritative - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Modifications of procedures of Draize et. al. according to - Category 8.3A (Category 1)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata