What is this ingredient?

미국 FDA 물질 등록 · UNII GMW67QNF9C · 등록명 Leucine · 단일 화학물질

Are there usage precautions?

피부 콜라겐 합성 도움 탄력 개선 효과 노화 방지와 피부 재생 효과 피부 장벽 강화 및 수분 유지

All ingredients

Ingredient Dictionary

LEUCINE

How much products actually contain

10 products state the amountmedian 0.000069%

under 0.01% 10
0.01–0.1% 0
0.1–1% 0
1% or more 0

Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.

Of the products containing it, 104 list it before the 1% line and 417 after it (usually 1% or less).

Products using this ingredient

12 of 519 confirmed · likeliest to carry enough first · See all 519

Definition

US FDA substance register · UNII GMW67QNF9C · registered name Leucine · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONINGSoftens hairHAIR CONDITIONINGReduces staticANTISTATIC

Safety & regulatory references

Reviewed by CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ロイシン: 本品は、次の化学式で表されるアミノ酸である。

Source: JCIA labelling names (Japan)

Names & identifiers

LEUCINEINCI류신Korean label name (MFDS standard)L-LeucineSynonymロイシンJapanese labelling name

CAS No.chemical registry number: 61-90-5
EC No.EU chemical inventory number: 200-522-0
DTXSIDUS EPA chemical ID: DTXSID9023203
DTXCIDUS EPA compound ID: DTXCID903203

IUPAC: L-Leucine
Molecular formula: C6H13NO2
Molecular weight: 131.175 g/mol

Measured properties

Appearance: Dry Powder · White solid, [Merck Index] White powder, [Sigma-Aldrich MSDS]
Boiling point: Sublimes at 145-148 °C. Decomposes at 293-295 °C (rapid heating, sealed tube)
Melting point: 293 °C · 268 - 288 °C
Solubility: 21500 mg/L (at 25 °C) · Leaflets from water. Sweet taste. Decomposes at 232 °C (also reported as 290 °C). Sublimes. pK1 = 2.36, pK2 = 9.60. Solubility in water (g/L): 7.97 (0 °C), 9.91 (25 °C), 14.06 (50 °C), 22.76 (75 °C), 42.06 (100 °C), in 90% alcohol: 1.3. Insoluble in ether. /Leucine DL-form/
Density: 1.293 g/cu cm at 18 °C
Dissociation constant: 2.38 · 9.61
Colour: White
Odour: Practically odorless
Melting/freezing point: 293 ℃
Vapour pressure: 0.0000000134 ㎜Hg (25degC)
Water solubility: 21500 g/100㎖ (25degC)
Relative density: 1.293
n-Octanol/water partition coefficient (Kow): -1.52
Molecular weight: 131.20

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 7 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Flavouring and nutrient4
Softener and conditioner2
Anti-static agent1

Source: US EPA CompTox dashboard