Definition
US FDA substance register · UNII V13007Z41A · registered name Lidocaine hydrochloride · single chemical substance
Lidocaine HCl is the organic compound that conforms to the formula
Cosmetic roles
No declared roleNOT REPORTED
Safety & regulatory references
Restriction II/399
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
LIDOCAINE HCLINCI
- CAS No.chemical registry number
- 6108-05-0
- DTXSIDUS EPA chemical ID
- DTXSID80209953
- DTXCIDUS EPA compound ID
- DTXCID30132444
- IUPAC
- N-(2,6-Dimethylphenyl)-N~2~,N~2~-diethylglycinamide--hydrogen chloride--water (1/1/1)
- Molecular formula
- C14H25ClN2O2
- Molecular weight
- 288.82 g/mol
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
Classed as moderate1
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- 822. Managing Burn Autograft Donor Site Pain Using Antimicrobial Bioresorbable Lidocaine-HCL Matrix: A Five-Patient Case Series · 2026
- Cold atmospheric plasma pretreatment combined with optimized liposomal formulation for enhanced transdermal delivery of lidocaine. · 2026
- HPMC/PVP K90 Dissolving Microneedles Fabricated from 3D-Printed Master Molds: Impact on Microneedle Morphology, Mechanical Strength, and Topical Dissolving Property · 2024
- Formulation and ex vivo skin permeation of lidocaine HCl topical gels using dillenia (Dillenia indica L.) fruit gum · 2020
- USE OF CASHEW BARK EXUDATE GUM IN THE PREPARATION OF 4 % LIDOCAINE HCL TOPICAL GELS · 2017