Gloshell
成分辞典

成分辞典

M-AMINOPHENOL

3-aminophenol is an aminophenol that is one of three amino derivatives of phenol which has the single amino substituent located meta to the phenolic -OH group.

韓国の配合上限
2.0%
分子構造

製品には実際どれくらい入っているか

この成分の含有量を表示した製品はまだありません。

この成分を含む製品のうち3件は全成分の前の方(1%ラインより前)、6件は後ろ(ふつう1%以下)に書いています。

この成分を含む製品

確認済み 9件中 9件 · 十分に入っている製品から

定義

3-aminophenol is an aminophenol that is one of three amino derivatives of phenol which has the single amino substituent located meta to the phenolic -OH group.

出典: PubChem

米国FDA 物質登録 · UNII L3WTS6QT82 · 登録名 m-Aminophenol · 単一の化学物質

出典: 米国FDA 物質識別番号(UNII)

化粧品での役割

髪を染めるHAIR DYEING

安全性・規制情報

制限
イギリス · 韓国

出典: ASEAN 化粧品指令 · EU 化粧品規則 · 韓国食薬処 化粧品規制情報 · 台湾FDA 化粧品成分 · 台湾FDA 化粧品規制 · 英国 化粧品規則

ASEAN

  • Field of application and/or use : Hair dye substance in oxidative hair dye products. Use for dyeing eyelashes and eyebrows is not permitted.
  • Other limitations and requirements : After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.2% The direction for use “wear suitable gloves” must be included in label or leaflet text.
  • Conditions of use and warning which must be printed on the labels : The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past Do not use to dye eyelashes or eyebrows

台湾

  • ※ 染髮產品之限量標準:係指該成分依產品使用說明書混合後之最高允許使用量。
  • ※ 化粧品之外包裝或容器,應明顯標示本表所列成分之注意事項。因外包裝或容器表面積過小或其他特殊情形致不能標示者,應於標籤、仿單或以其他方式刊載之。
  • ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
  • ※ 化粧品宣稱效能者,須符合化粧品標示宣傳廣告涉及虛偽誇大或醫療效能認定準則規定。
  • 用途 : 使用限制
  • 最大配合量 : 氧化性染髮產品 : 1.2%

中国

  • 最大配合量 : 1%

欧州連合

  • Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes
  • Other : For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1,2 % (b) For professional use only
  • Wording of conditions of use and warnings : (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy.Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (b) To be printed on the label: The mixing ratio. “For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes,— has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them.”

出典: 韓国食薬処 化粧品規制情報

韓国の有害物質GHS分類なし · 既存化学物質

出典: 韓国 有害物質GHS情報(環境公団)

Restriction III/217 · Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Opinion on m-Aminophenol

出典: EU CosIng 成分リスト

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2005/2006

出典: 米国CIR 安全性評価

Reviewed by CIR: Final Report on the Safety Assessment of p-Aminophenol, m-Aminophenol, and o-Aminophenol

出典: 米国CIR 安全性評価

詳しい資料 — 表示名・識別番号・物性・試験記録・文献

別名・識別情報

M-AMINOPHENOLINCIm-아미노페놀韓国の表示名(食薬処標準名)Phenol, 3-amino-別名
CAS No.化学物質登録番号
591-27-5
EC No.EU化学物質目録番号
209-711-2
DTXSID米国EPA化学物質番号
DTXSID3024497
DTXCID米国EPA化合物番号
DTXCID704497
IUPAC
3-Aminophenol
分子式
C6H7NO
分子量
109.128 g/mol

測定された物性

性状
M-aminophenol appears as white crystals or off-white flakes. (NTP, 1992) · Large Crystals, Liquid
沸点
327 °F at 11 mmHg (NTP, 1992) · 164 °C at 11 mm Hg
融点
253 to 259 °F (NTP, 1992) · 123 °C
溶解性
1 to 10 mg/mL at 75 °F (NTP, 1992) · Freely soluble in amyl alcohol and hot water, soluble in 40 parts cold water, very slightly soluble in petroleum ether
密度
1.195 g/cu cm
解離定数
pK1 = 4.37 at 20 °C, pK2 = 9.815 at 20 °C (conjugate acid)
色
白色
融点・凝固点
122~123 ℃
初留点および沸点範囲
164 ℃(at 11 ㎜Hg)
引火点
92 ℃
蒸気圧
0.0096 ㎜Hg (at 25 ℃)
溶解度
27000 ㎎/ℓ (at 20 ℃)
比重
1.195
n-オクタノール/水分配係数(Kow)
0.21 (at pH 5.6)
分子量
109.12

物質そのものを測定した値です。安全保健公団(KOSHA)の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。

出典: PubChem · 韓国安全保健公団 SDS

製品が実際に使っている用途

米国EPAにこの成分を届け出た製品8件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。

  • Dye5
  • Intermediate2
  • Monomers1

出典: 米国EPA CompTox

刺激・感作試験の記録

皮膚試験8件・眼試験3件の記録があります。

刺激が強いと分類4件低いと分類4件

試験ごとに結論が分かれています(最も多い結論の割合 50%)。この成分が刺激性だとは言い切れないということです。 原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。

試験11件をすべて見る
  • Not classified
    Skin Irritation · Screening
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline:
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · other guideline: according to
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • Classification not possible
    Skin Sensitization · Screening
  • Sh
    Skin Sensitization · Authoritative
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · according to other guideline:
  • Classification not possible
    Eye Irritation · Screening
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · other guideline: according to

出典: 米国EPA CompTox

関連文献

連携データベース 27